Laboratory of Genomics and Proteomics of Disease Vectors

List of all publications

Found: 16 records

• Francischetti I.M., Oliveira C.J., Ostera G.R., Yager S.B., Debierre-Grockiego F., Carregaro V., Jaramillo-Gutierrez G., Hume J.C., Jiang L., Moretz S.E., Lin C.K., Ribeiro J.M., Long C.A., Vickers B.K., Schwarz R.T., Seydel K.B., Iacobelli M., Ackerman H.C., Srinivasan P., Gomes R.B., Wang X., Monteiro R.Q., Kotsyfakis M., Sá-Nunes A., Waisberg M. (2012) Defibrotide Interferes With Several Steps of the Coagulation-Inflammation Cycle and Exhibits Therapeutic Potential to Treat Severe Malaria. Arteriosclerosis, Thrombosis, and Vascular Biology 32: 786–798.

  DOI: 10.1161/ATVBAHA.111.240291

• Horká H., Staudt V., Klein M., Taube Ch., Reuter S., Dehzad N., Andersen J.F., Kopecký J., Schild H., Kotsyfakis M., Hoffmann M., Gerlitzki B., Stassen M., Bopp T., Schmitt E. (2012) The tick salivary protein Sialostatin L inhibits the Th9-derived production of the asthma-promoting cytokine IL-9 and is effective in the prevention of experimental asthma. Journal of Immunology 188: 2669–2676. (link)

  DOI: 10.4049/​jimmunol.1100529

• Rodrigues J., Oliveira G.A., Kotsyfakis M., Dixit R., Molina-Cruz A., Jochim R., Barillas-Mury C. (2012) An epithelial serine protease, AgESP, is required for Plasmodium invasion in the mosquito Anopheles gambiae. PLoS ONE 7: e35210. (link)

  DOI: 10.1371/journal.pone.0035210

• Tsujimoto H., Kotsyfakis M., Francischetti I.M.B., Eum J.H., Strand M.R., Champagne D.E. (2012) Simukunin from the salivary glands of the black fly Simulium vittatum inhibits enzymes that regulate clotting and inflammatory responses. PLoS ONE 7: e29964. (link)

  DOI: 10.1371/journal.pone.0029964

• Calvo E., Mizurini D.M., Sa-Nunes A., Ribeiro J.M., Andersen J.F., Mans B.J., Monteiro R.Q., Kotsyfakis M., Francischetti I.M. (2011) Alboserpin, a factor Xa inhibitor from the mosquito vector of yellow fever, binds heparin and membrane phospholipids and exhibits antithrombotic activity. Journal of Biological Chemistry 286: 27998–28010.

  DOI: 10.1074/jbc.M111.247924

• Chmelař J., Oliveira C.J., Řezáčová P., Francischetti I.M., Kovářová Z., Pejler G., Kopáček P., Ribeiro J.M., Mareš M., Kopecký J., Kotsyfakis M. (2011) A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation. Blood 117: 736–744.

  DOI: 10.1182/blood-2010-06-293241

• Schwarz A., Juarez J.A., Richards J., Rath B., Machaca V.Q., Castro Y.E., Málaga E.S., Levy K., Gilman R.H., Bern C., Verastegui M., Levy M.Z. (2011) Anti-triatomine saliva immunoassays for the evaluation of impregnated netting trials against Chagas disease transmission. International Journal for Parasitology 41: 591–594.

  DOI: 10.1016/j.ijpara.2011.02.001

• Sojka D., Francischetti I.M., Calvo E., Kotsyfakis M. (2011) Cysteine proteases from bloodfeeding arthropod ectoparasites. Advances in experimental medicine and biology 712: 177–191.

  DOI: 10.1007/978-1-4419-8414-2_11

• Francischetti I.M.B., Kotsyfakis M., Andersen J. F., Lukszo J. (2010) Cyr61/CCN1 Displays High-Affinity Binding to the Somatomedin B (1-44) Domain of Vitronectin. PLoS ONE 5: e9356.

  DOI: 10.1371/journal.pone.0009356

• Kotsyfakis M., Horká H., Salát J., Andersen J.F. (2010) The crystal structures of two salivary cystatins from the tick Ixodes scapularis and the effect of these inhibitors on the establishment of Borrelia burgdorferi infection in a murine model. Molecular Microbiology 77: 456–470.

  DOI: 10.1111/j.1365-2958.2010.07220.x

• Kovářová Z., Chmelař J., Šanda M., Brynda J., Mareš M., Řezáčová P. (2010) Crystallization and diffraction analysis of the serpin IRS-2 from the hard tick Ixodes ricinus. Acta Crystallographica Section F 66: 1453–1457.

  DOI: 10.1107/S1744309110032343

• Mendoza-Franco E.F., Scholz T., Rozkošná P. (2010) Tucunarella n. gen. and other Dactylogyrids (Monogenoidea) from cichlid fish (Perciformes) from Peruvian Amazonia. Journal of Parasitology 96: 491–498.

  DOI: 10.1645/GE-2213.1

• Salát J., Paesen G.C., Řezáčová P., Kotsyfakis M., Kovářová Z., Šanda M., Majtán J., Grunclová L., Horká H., Andersen J.F., Brynda J., Horn M., Nunn M.A., Kopáček P., Kopecký J., Mareš M. (2010) Crystal structure and functional characterization of an immunomodulatory salivary cystatin from the soft tick Ornithodoros moubata. Biochemical Journal 429: 103–112.

  DOI: 10.1042/BJ20100280

• Schwarz A., Medrano-Mercado N., Billingsley P.F., Schaub G.A., Sternberg J.M. (2010) IgM-antibody responses of chickens to salivary antigens of Triatoma infestans as early biomarkers for low-level infestation of triatomines. International Journal for Parasitology 40: 1295–1302.

  DOI: 10.1016/j.ijpara.2010.03.013

• CHMELAŘ J., KOPECKÝ J., ANDERSON J.M., VALENZUELA J.G., JOCHIM R.C., MU J. (2008) Insight into the sialome of the castor bean tick, Ixodes ricinus. BMC Genomics 20: 233-0.

  DOI: 10.1186/1471-2164-9-233

• SALÁT J., JELÍNEK J., CHMELAŘ J., KOPECKÝ J. (2008) Efficacy of gamma interferon and specific antibody for treatment of microsporidiosis caused by Encephalitozoon cuniculi in SCID mice. Antimicrobial Agents and Chemotherapy 52: 2169-2174.

  DOI: 10.1128/AAC.01506-07

Sections > Ticks and Tick-Borne Diseases > Laboratory of Genomics and Proteomics of Disease Vectors > List of publications