Laboratory of Vector Immunology

List of all publications

Found: 31 records

• Kopáček P., Hajdušek O., Burešová V. (2012) Tick as a model for the study of a primitive complement system. Advances in Experimental Medicine and Biology 710: 83–93.

  DOI: 10.1007/978-1-4419-5638-5_9

• Burešová V., Hajdušek O., Franta Z., Loosová G., Grunclová L., Levashina E.A., Kopáček P. (2011) Functional genomics of tick thioester-containing proteins reveal the ancient origin of the complement system. Journal of Innate Immunity 3: 623–630.

  DOI: 10.1159/000328851

• Chmelař J., Oliveira C.J., Řezáčová P., Francischetti I.M., Kovářová Z., Pejler G., Kopáček P., Ribeiro J.M., Mareš M., Kopecký J., Kotsyfakis M. (2011) A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation. Blood 117: 736–744.

  DOI: 10.1182/blood-2010-06-293241

• Franta Z., Sojka D., Frantová H., Dvořák J., Horn M., Srba J., Talacko P., Mareš M., Schneider E., Craik C.S., McKerrow J.H., Caffrey C.R., Kopáček P. (2011) IrCL1-The haemoglobinolytic cathepsin L of the hard tick, Ixodes ricinus. International Journal for Parasitology 41: 1253–1262.

  DOI: 10.1016/j.ijpara.2011.06.006

• Sojka D., Francischetti I.M., Calvo E., Kotsyfakis M. (2011) Cysteine proteases from bloodfeeding arthropod ectoparasites. Advances in experimental medicine and biology 712: 177–191.

  DOI: 10.1007/978-1-4419-8414-2_11

• Franta Z., Frantová H., Konvičková J., Horn M., Sojka D., Mareš M., Kopáček P. (2010) Dynamics of digestive proteolytic system during blood feeding of the hard tick Ixodes ricinus. Parasites & Vectors 3: 119.

  DOI: 10.1186/1756-3305-3-119

• Hajdušek O., Almazán C., Loosová G., Villar M., Canales M., Grubhoffer L., Kopáček P., de la Fuente J. (2010) Characterization of ferritin 2 for the control of tick infestations. Vaccine 28: 2993–2998.

  DOI: 10.1016/j.vaccine.2010.02.008

• Salát J., Paesen G.C., Řezáčová P., Kotsyfakis M., Kovářová Z., Šanda M., Majtán J., Grunclová L., Horká H., Andersen J.F., Brynda J., Horn M., Nunn M.A., Kopáček P., Kopecký J., Mareš M. (2010) Crystal structure and functional characterization of an immunomodulatory salivary cystatin from the soft tick Ornithodoros moubata. Biochemical Journal 429: 103–112.

  DOI: 10.1042/BJ20100280

• Štefanič S., Dvořák J., Horn M., Braschi S., Sojka D., Ruelas D., Suzuki B., Lim K.-C., Hopkins S.D., McKerrow J.H., Caffrey C.R. (2010) RNA Interference in Schistosoma mansoni Schistosomula: Selectivity, Sensitivity and Operation for Larger-Scale Screening. PLoS Neglected Tropical Diseases 4: e850.

  DOI: 10.1371/journal.pntd.0000850

• BUREŠOVÁ V., HAJDUŠEK O., FRANTA Z., SOJKA D., KOPÁČEK P. (2009) IrAM-An alpha2-macroglobulin from the hard tick Ixodes ricinus: characterization and function in phagocytosis of a potential patogen Chryseobacterium indologenes Developmental and Comparative Immunology 33: 489-498.

  DOI: 10.1016/j.dci.2008.09.011

• HAJDUŠEK O., SOJKA D., KOPÁČEK P., BUREŠOVÁ V., FRANTA Z., ŠAUMAN I., WINZERLING J., GRUBHOFFER L. (2009) Knockdown of proteins involved in iron metabolism limits tick reproduction and development. Proceedings of the National Academy of Sciences 109: 1033-1038.

  DOI: 10.1073/pnas.0807961106

• HORN M., NUSSBAUMEROVÁ M., ŠANDA M., KOVÁŘOVÁ Z., SRBA J., FRANTA Z., SOJKA D., BOGYO M., CAFFREY C.R., KOPÁČEK P., MAREŠ M. (2009) Hemoglobin digestion in blood-feeding ticks: mapping a multipeptidase pathway by functional proteomics. Chemistry & Biology 16: 1053-1063.

  DOI: 10.1016/j.chembiol.2009.09.009

• OVAT A., MUINDI F., FAGAN C., BROUNER M., HANSELL E., DVOŘÁK J., SOJKA D., KOPÁČEK P., MCKERROW J.H., CAFFREY C.R., POWERS J.C. (2009) Aza-peptidyl Michael acceptor and epoxide inhibitors-potent and selective inhibitors of Schistosoma mansoni and Ixodes ricinus legumains (asparaginyl endopeptidases). Journal of Medicinal Chemistry 52: 7192-7210.

  DOI: 10.1021/jm900849h

• GÖTZ M.G., JAMES K.E., HANSELL E., DVOŘÁK J., SESHAADRI A., SOJKA D., KOPÁČEK P., MCKERROW J.H., CAFFREY C.R., POWERS J.C. (2008) Aza-peptidyl Michael acceptors. A new class of potent and selective inhibitors of asparaginyl endopeptidases (legumains) from evolutionarily diverse pathogens. Journal of Medicinal Chemistry 51: 2816-2832.

  DOI: 10.1021/jm701311r

• MAN P., KOVÁŘ V., ŠTĚRBA J., STROHALM M., KAVAN D., KOPÁČEK P., GRUBHOFFER L., HAVLÍČEK V. (2008) Deciphering Dorin M glycosylation by mass spectrometry. European Journal of Mass Spectrometry 14: 345-354.

• SOJKA D., FRANTA Z., HORN M., HAJDUŠEK O., CAFFREY C.R., MAREŠ M., KOPÁČEK P. (2008) Profiling of proteolytic enzymes in the gut of the tick Ixodes ricinus reveals an evolutionarily conserved network of aspartic and cysteine peptidases. Parasites & Vectors: 0-0.

  DOI: 10.1186/1756-3305-1-7

• SOJKA D., HAJDUŠEK O., DVOŘÁK J., SAJID M., FRANTA Z., SCHNEIDER E.L., CRAIK C.S., VANCOVÁ M., BUREŠOVÁ V., BOGYO M., SEXTON K.B., MC KERROW J.H., CAFFREY C.R., KOPÁČEK P. (2007) IrAE – An asparaginyl endopeptidase (legumain) in the gut of the hard tick Ixodes ricinus. International Journal for Parasitology 37: 713-724.

  DOI: 10.1016/j.ijpara.2006.12.020

• BUREŠOVÁ V., FRANTA Z., KOPÁČEK P. (2006) A comparison of Chryseobacterium indologenes pathogenicity to the soft tick Ornithodoros moubata and hard tick Ixodes ricinus. Journal of Invertebrate Pathology 93: 96-104.

  DOI: 10.1016/j.jip.2006.05.006

• GRUNCLOVÁ L., HORN M., VANCOVÁ M., SOJKA D., FRANTA Z., MAREŠ M., KOPÁČEK P. (2006) Two secreted cystatins of the soft tick Ornithodoros moubata: differential expression pattern and inhibitory specificity. Biological Chemistry 387: 1635-1644.

  DOI: 10.1515/BC.2006.204

• REGO R.O.M., KOVÁŘ V., KOPÁČEK P., WEISE C., MAN P., ŠAUMAN I., GRUBHOFFER L. (2006) The tick plasma lectin, Dorin M, is a fibrinogen-related molecule. Insect Biochemistry and Molecular Biology 36: 291-299.

  DOI: 10.1016/j.ibmb.2006.01.008

• REGO R.O.M., HAJDUŠEK O., KOVÁŘ V., KOPÁČEK P., GRUBHOFFER L., HYPŠA V. (2005) Molecular cloning and comparative analysis of fibrinogen-related proteins from the soft tick Ornithodoros moubata and the hard tick Ixodes ricinus. Insect Biochemistry and Molecular Biology 35: 991-1004.

  DOI: 10.1016/j.ibmb.2005.04.001

• GRUNCLOVÁ L., FOUQUIER H., HYPŠA V., KOPÁČEK P. (2003) Lysozyme from the gut of the soft tick Ornithodoros moubata: the sequence, phylogeny and post-feeding regulation. Developmental and Comparative Immunology 27: 651-660.

  DOI: 10.1016/S0145-305X(03)00052-1

• KOPÁČEK P., ŽDYCHOVÁ J., YOSHIGA T., WEISE C., RUDENKO N., LAW J.H. (2003) Molecular cloning, expression and isolation of ferritins from two tick species – Ornithodoros moubata and Ixodes ricinus. Insect Biochemistry and Molecular Biology 33: 103-113.

  DOI: 10.1016/S0965-1748(02)00181-9

• SARAVANAN T., WEISE CH., SOJKA D., KOPÁČEK P. (2003) Molecular cloning, structure and bait-region splice variants of ?2-macroglobulin from the soft tick Ornithodoros moubata. Insect Biochemistry and Molecular Biology 33: 841-851.

  DOI: 10.1016/S0965-1748(03)00083-3

• LOOSOVÁ G., JINDRÁK L., KOPÁČEK P. (2001) Mortality caused by experimental infection with the yeast Candida haemulonii in the adults of Ornithodoros moubata (Acarina: Argasidae). Folia Parasitologica 48: 149-153.

• KOPÁČEK P., WEISE CH., SARAVANAN T., VÍTOVÁ K., GRUBHOFFER L. (2000) Characterization of an ?-macroglobulin-like glycoprotein isolated from the plasma of the soft tick Ornithodoros moubata. European Journal of Biochemistry 267: 465-475.

• KOVÁŘ V., KOPÁČEK P., GRUBHOFFER L. (2000) Isolation and characterization of Dorin M, a lectin from plasma of the soft tick Ornithodoros moubata. Insect Biochemistry and Molecular Biology 30: 195-205.

• KOPÁČEK P., VOGT R., JINDRÁK L., WEISE C., ŠAFAŘÍK I. (1999) Purification and characterization of the lysozyme from the gut of the soft tick Ornithodoros moubata. Insect Biochemistry and Molecular Biology 29: 989-997.

• WEDDE M., WEISE C., KOPÁČEK P., FRANKE P., VILCINSKAS A. (1998) Purification and characterization of an inducible metalloprotease inhibitor from the hemolymph of greater wax moth larvae, Galleria mellonella. European Journal of Biochemistry 255: 535-543.

• WEISE C., FRANKE P., KOPÁČEK P., WIESNER A. (1998) Primary structure of apolipophorin-III from the greater wax moth, Galleria mellonella. Journal of Protein Chemistry 17: 633-641.

• VILCINSKAS A., KOPÁČEK P., JEGOROV A., VEY A., MATHA V. (1997) Detection of Lipophorin as the Major Cyclosporin-Binding Protein in the hemolymph of the Greater Wax Moth Galleria mellonella. Comparative Biopchemystry and Physiology 117: 41-45.

  DOI: 10.1016/S0742-8413(96)00235-6

Sections > Ticks and Tick-Borne Diseases > Laboratory of Vector Immunology > List of publications