MVDr. Alejandro Cabezas-Cruz

Job Position: PostDoc - Laboratory of Arbovirology

Contact details

E-mail: alejandrocabezascruz@yahoo.es
Room: 302

Curriculum vitae

 

PERSONAL DETAILS

Address: Branišovská 31, 370 05 České Budějovice, Czech Republic.

Phone (mobile): +420 775 935 953

E-mail: cabezasalejandrocruz@gmail.com

Date of Birth: 14.01.1983

 

PROFESSIONAL EXPERIENCE

February 2017-present: UMR BIPAR, Animal Health Laboratory, ANSES, INRA, ENVA, Maisons Alfort, France

Function: Chargé de Recherche de 1ère classe

 

October 2016-present: Faculty of Science, University of South Bohemia, České Budějovice, Czech Republic

Function: Head of Laboratory

 

October 2016-present: Institute of Parasitology, České Budějovice, Czech Republic

Function: Researcher

 

2011: Charité - Universitätsmedizin Berlin, Berlin, Germany

Function: Internship in the laboratory of Dr. Sophie Van Linthout

Topic: Cell culture and molecular biology

 

2010: University of Oxford, UK

Function: Visiting Scientist in the laboratory of Prof. Pat Nuttall

Topic: Functional characterization of tick molecules with immune modulator effect

 

2006 – 2010: Center for Genetic Engineering and Biotechnology (CIGB), Cuba

Function: Researcher

Topic: Development of recombinant vaccines against the cattle tick Rhipicephalus microplus

 

2001 – 2006: Centre of Molecular immunology (CIM), Cuba

Function: Internship in the laboratory of Dr. Enrique Montero

Topic: Immunology and animal models

 

EDUCATION

10.2013 –09.10.2016: PhD in molecular and cellular aspects of biology

University of Lille 2, Institut Pasteur de Lille, Lille, France. Très honorable avec felicitations" Degree

Dr. Raymond Pierce

 

01.2014 – 10.10.2014: PhD in basic and applied research in natural resources

University of Castilla-La Mancha (UCLM), Ciudad Real, Spain. Honors Degree (Cum Laude)

Prof. José de la Fuente

 

04.2012 – 09.2013: Master in Parasitology, MSc

University of South Bohemia, České Budějovice, Czech Republic. Honors Degree

Prof. Libor Grubhoffer

 

09.2001 – 06.2006: Doctor of Veterinary Medicine, DVM

Agricultural University of Havana (UNAH), Havana, Cuba. Honors Degree

Dr. Dasha Fuentes Morales

 

POSTGRADUATED COURSES

10.2008 – 02. 2009: Biochemical Methods, College of Biological Sciences, University of Havana, Cuba.

 

06. 2008 – 10.2008: Enzymology, College of Biological Sciences, University of Havana, Cuba.

 

03. 2008 – 06.2008: Bio-molecules, College of Biological Sciences, University of Havana, Cuba.

 

INVITED PRESENTATIONS

2017: Justus Liebig University Giessen, Giessen, Germany

Institute of Hygiene and Tropical Medicine, Lisbon, Portugal

Veterinary Research Institute, Brno, Czech Republic

South Bohemia University, České Budějovice, Czech Republic

2016: Federal Research Institute for Animal Health, Jena, Germany

2015: Institute of Hygiene and Tropical Medicine, Lisbon, Portugal

 

CONTRIBUTION AS REVIEWER

2014 – present: Vaccine, BioMed Research International, Infection Genetics and Evolution, Ticks and Tick-borne Diseases, Revista brasileira de parasitologia veterinaria, Veterinary Parasitology, Letters in Applied Microbiology, Parasites & Vectors, Medical and Veterinary Entomology

 

COMPETITIVE FUNDING

2013 – 2016: Doctoral Scholarship, University of Lille 2 (€ 46 800)

 

2012 – 2013: Early Stage Researcher, Marie Skłodowska-Curie Scholarship (€ 81 022)

 

 

AWARDS

2017: Award, Odile Bain Memorial Prize (OBMP)

           Award, Marie Sklodowska-Curie Actions Seal of Excellence.

 

2015: Outstanding Reviewer Award, Ticks and Tick-borne Diseases

 

2012: Marie Skłodowska-Curie Early Stage Researcher Scholarship

 

2010: Award, Cuban Academy of Sciences

 

 TEACHING & MENTORING

2017: Trainer, “Phylogenetic and population genetic tools for the study of vectors and vector-borne pathogens”, Training School. European Network for Neglected Vectors and Vector-Borne Infections, Lisbon, Portugal

Training on phylogenetic analysis for Master project of Myriam Denoual

 

2016: Training on phylogenetic analysis for Master project of Jordi Nelis

 

2012 – 2013: Assistance and training on bioinformatics and molecular biology for PhD project of Miray Tonk

 

2007 – 2010: Supervision of Undergraduate Project of Pedro Enrique

 

2002 – 2003: Teaching assistant at the Agricultural University of Havana for first year BSc students (60h per year)

courses in ‘Histology’, ‘General Anatomy’ and ‘Comparative Anatomy’.

 

Thesis Direction

2017 – Present: Co-director of PhD Thesis. Pedro Jose Espinosa Prados.

Institution: University of Castilla-La Mancha, Spain

Thesis: Host-pathogen interactions in Anaplasma phagocytophilum.

 

2016 – Present: Director of Undergraduate Thesis of Sewmi Madu, Hellen Chemtai and Julia Gobl

Institution: University of South Bohemia, Czech Republic

Thesis: Role of Histone Modifying Enzymes in the embryogenesis of the soft tick Ornithodoros moubata.

 

MEMBER OF THESIS JURY

2016 Lisa Hain, Bachelor Thesis.

Institution: University of South Bohemia, Czech Republic.

Thesis: Understanding the role of bb0454 during infection by Borrelia afzelii.

 

CONFERENCE/WORKSHOP PRESENTATIONS/POSTERS

2017: IX International Conference on Ticks and Tick-borne Pathogens (TTP-9), Cairns, Australia

           International Congress on Rickettsia and other Intracellular Bacteria (ESCCAR) 2017, Marseille, France

 

2016: Workshop on Arthropod-Borne Diseases, Jena, Germany (ORAL)

 

2015: Molecular and Cellular Biology of Helminths IX, Hydra, Greece (POSTER)

 

2014: VIII International Conference on Ticks and Tick-borne Pathogens (TTP-8), Cape Town, South Africa (POSTER)

 

2013: II Tick-borne diseases workshop, Berlin, Germany.

           International Symposium on Ectoparasites of Pets (ISEP) conference 2013, Munich, Germany

           XII. International Jena Symposium on Tick-Borne Diseases, Jena, Germany

 

2012: POSTICK immunology worshop, Research Center Borstel, Borstel, Germany

           Joint conference on emerging and remerging epidemics affecting global health, Orvieto, Italy

           Euroscience Open Forum (ESOF) and Marie Curie Actions Conferences, Dublin, Ireland

           I Tick-borne diseases workshop, Berlin, Germany.

           POSTICK bioinformatics workshop, University of Glasgow Veterinary School, Glasgow, UK

 

PUBLICATIONS

 

2017

  1. Cabezas Cruz A., et al. 2017. Immunological basis of tick-induced allergy to red meat. Trends in Parasitology. S1471-4922(17)30069-7. doi: 10.1016/j.pt.2017.03.004.
  2. Cabezas-Cruz A., et al. 2017. Effect of blood type on anti-α-Gal immunity and the incidence of infectious diseases. Experimental and Molecular Medicine. 49 (3): e301.
  3. Cabezas-Cruz A., et al. 2017. Anaplasma phagocytophilum infection subverts carbohydrate metabolic pathways in the tick vector, Ixodes scapularis. Frontiers in Cellular and Infection Microbiology. 7:23.
  4. Cabezas-Cruz A., et al. 2017. Remodeling of tick cytoskeleton in response to infection with Anaplasma phagocytophilum. Frontiers in Bioscience. 22(11):1830-1844.
  5. Cabezas-Cruz A., et al. 2017. Tick-pathogen ensembles: do molecular interactions lead ecological innovation? Frontiers in Cellular and Infection Microbiology. 7:74.
  6. de la Fuente J., Antunes S., Bonnet S., Cabezas-Cruz A., et al. 2017. Tick-pathogen interactions and vector competence: identification of molecular drivers for tick-borne diseases. Frontiers in Cellular and Infection Microbiology. 7:114.
  7. Mateos-Hernández L., Villar M., Moral A., Rodríguez C G., Arias T A., de la Osa V., Brito  F F., Fernández de Mera I G., Alberdi P., Ruiz-Fons F., Cabezas-Cruz A., et al. 2017. Tick-host conflict: Immunoglobulin E antibodies to tick proteins in patients with anaphylaxis to tick bite. Oncotarget. doi: 10.18632/oncotarget.15243.

 

2016

  1. Cabezas-Cruz A., et al. 2016. Antiplasmodial activity is an ancient and conserved feature of tick defensins. Frontiers in Microbiology. 7:1682.
  2. Cabezas-Cruz A., et al. 2016. Be aware of ticks when strolling through the park. Frontiers for Young Minds. 4(24).
  3. Cabezas-Cruz A., et al. 2016. Control of vector-borne infectious diseases by human immunity against α-Gal. Expert Review of Vaccines. 15(8):953-955.
  4. Cabezas-Cruz A., et al. 2016. Anaplasma phagocytophilum increases the levels of histone modifying enzymes to inhibit cell apoptosis and facilitate pathogen infection in the tick vector, Ixodes scapularis. Epigenetics. 11(4):303-19. Figure selected for “Cover art” of Vol. 11, 2016, Epigenetics.
  5. Cabezas-Cruz A., et al. 2016. Ehrlichia minasensis sp. nov., isolated from the tick Rhipicephalus microplus. International Journal of Systematic and Evolutionary Microbiology. 66:1426-1430.
  6. Valdés J J*., Cabezas-Cruz A*., et al. 2016. Substrate prediction of Ixodes ricinus salivary lipocalins differentially expressed during Borrelia afzelii infection. Scientific Reports. 6:32372. *Joint first authors.
  7. Tellier G., Lenne A., Cailliau-Maggio K., Cabezas-Cruz A., et al. 2016. Identification of Plasmodium falciparum translation initiation 1 eIF2β subunit: direct interaction with Protein Phosphatase type 1. Frontiers in Microbiology. 7:777.
  8. de la Fuente J., Villar M., Cabezas-Cruz A., et al. 2016. Tick-host-pathogen interactions: conflict and cooperation. PLoS Pathogens. 12(4): e1005488.
  9. Estrada-Peña A., de la Fuente J., Cabezas-Cruz A. 2016. A comparison of the performance of regression models of Amblyomma americanum (L.)  (Ixodidae) using life cycle or landscape data from administrative divisions. Ticks and tick-borne diseases. 7(4):624-30.
  10. Ferrolho J., Antunes S., Santos A S., Velez R., Padre L., Cabezas-Cruz A., et al. 2016. Detection and phylogenetic characterization of Theileria spp. and Anaplasma marginale in Rhipicephalus bursa in Portugal. Ticks and tick-borne diseases. 7(3): 443–448.
  11. de la Fuente J., Villar M., Estrada-Peña A., Cabezas-Cruz A., et al. 2016. Anaplasma phagocytophilum uses similar strategies to establish infection in tick vectors and vertebrate hosts. Trends in Microbiology. 24(3): 173–180.
  12. Almazán C., González-Álvarez H., García-Fernández I., Cabezas-Cruz A., et al. 2016. Molecular identification and characterization of Anaplasma platys and Ehrlichia canis in dogs in Mexico. Ticks and tick-borne diseases. 7(2):276-283.
  13. Noda A A., Rodríguez I., Miranda J., Mattar S., Cabezas-Cruz A. 2016. First Report of Spotted Fever Group Rickettsia in Cuba. Ticks and Tick-borne Diseases. 7 (2016): 1057–1058.
  14. Espinosa P J., Alberdi P., Cabezas-Cruz A., et al. 2016. Anaplasma phagocytophilum manipulates host cell apoptosis by different mechanisms to establish infection. Veterinary Sciences. 3(15): vetsci3030015.
  15. Villar M., López V., Ayllón N., Cabezas-Cruz A., et al. 2016. The intracellular bacterium Anaplasma phagocytophilum selectively manipulates the levels of vertebrate host proteins in the tick vector Ixodes scapularis. Parasites & Vectors. 9:467.
  16. Estrada-Peña A., Sprong H., Cabezas-Cruz A., et al. 2016. Nested coevolutionary networks shape the ecological relationships of ticks, hosts and the Lyme disease bacteria, Borrelia burgdorferi. Parasites & Vectors. 9:517.

 

2015

  1. Cabezas-Cruz A., et al. 2015. Regulation of the immune response to α-gal and vector-borne diseases. Trends in Parasitology. 31(10): 470-476.
  2. Cabezas-Cruz A., et al. 2015. Fast evolutionary rates associated with functional loss in class I glucose transporters of Schistosoma mansoni. BMC Genomics. 16(1):980.
  3. Cabezas-Cruz A & de la Fuente J. 2015. Anaplasma marginale major surface protein 1a: a marker of strain diversity with implications for control of bovine anaplasmosis. Ticks and tick-borne diseases. 6(2015):205-210.
  4. Cabezas-Cruz A., et al. 2015. Complete Genome Sequence of Ehrlichia mineirensis, a Novel Organism Closely Related to Ehrlichia canis with a New Host Association. Genome Announcement. 3(1):e01450-14.
  5. Tonk M*., Cabezas-Cruz A*., et al. 2015. Ixodes ricinus defensins attack distantly-related pathogens. Developmental & Comparative Immunology. 53(2):358-365. *Joint first authors.
  6. Lancelot J., Cabezas-Cruz A., et al. 2015. Schistosome sirtuins as drug targets. Future Medicinal Chemistry. 7(6): 765-782.
  7. Alberdi P., Ayllón N., Cabezas-Cruz A., et al. 2015. Infection of Ixodes spp. tick cells with different Anaplasma phagocytophilum isolates induces the inhibition of apoptotic cell death. Ticks and tick-borne diseases. 6(6):758-767.
  8. Tonk M., Knorr E., Cabezas-Cruz A., et al. 2015. Tribolium castaneum defensins are primarily active against Gram-positive bacteria. Journal of invertebrate pathology. 132: 208-215.
  9. Kocan K M., de la Fuente J., Cabezas-Cruz A. 2015. The genus Anaplasma: New challenges after reorganization. Revue Scientifique et technique (International Office of Epizootics). 34(2):577-586.
  10. Estrada-Peña A., de la Fuente J., Ostfeld R., Cabezas-Cruz A. 2015. Interactions between tick and transmitted pathogens evolved to minimise competition through nested and coherent networks. Scientific Reports. 5: 10361.
  11. Ayllón N., Villar M., Galindo R C., Kocan K M., Šíma R., López J., Vázquez J., Alberdi P., Cabezas-Cruz A., et al. 2015. Systems Biology of Tissue-Specific Response to Anaplasma phagocytophilum Reveals Differentiated Apoptosis in the Tick Vector Ixodes scapularis. PLoS Genetics. 11(3): e1005120.
  12. Lis K., Fernández de Mera I G., Popara M., Nieves A., Cabezas-Cruz A., et al. 2015. Molecular and immunological characterization of three strains of Anaplasma marginale grown in cultured tick cells. Ticks and tick-borne diseases. 6(2015):522-529.
  13. de la Fuente J., Díez-Delgado I., Contreras M., Vicente J., Cabezas-Cruz A., et al. 2015. Complete genome sequence of field isolates of Mycobacterium bovis and Mycobacterium caprae. Genome Announcement. 3(3):e00247-15.
  14. Baêta B A., Ribeiro Carla C D U., Teixeira R C., Cabezas-Cruz A., et al. 2015. Characterization of two strains of Anaplasma marginale isolated from cattle in Rio de Janeiro, Brazil, after propagation in tick cell culture. Ticks and tick-borne diseases. 6(2):141-145.
  15. Ayllón N., Naranjo V., Hajdušek O., Villar M., Galindo R C., Kocan K M., Alberdi P., Šíma R., Cabezas-Cruz A., et al. 2015. Nuclease Tudor-SN is involved in tick dsRNA-mediated RNA interference and feeding but not in defense against flaviviral or Anaplasma phagocytophilum rickettsial infection. PLoS ONE. 10(7):e0133038.
  16. Villar M., Ayllon N., Kocan K M., Bonzon-Kulichenko E., Alberdi P., Blouin E F., Weisheit S., Mateos-Hernandez L., Cabezas-Cruz A., et al. 2015. Identification and characterization of Anaplasma phagocytophilum proteins involved in infection of the tick vector, Ixodes scapularis. PLoS ONE. 10(9):e0137237.
  17. Pinheiro-Silva R., Borges L., Coelho L P., Cabezas-Cruz A., et al. 2015. Gene expression changes in the salivary glands of Anopheles coluzzii elicited by Plasmodium berghei infection. Parasites & Vectors. 8:485.
  18. de la Fuente J., Estrada-Peña A., Cabezas-Cruz A., et al. 2015. Flying ticks: Anciently evolved associations that constitute a risk of infectious disease spread. Parasites & Vectors. 8:538.
  19. de la Fuente J., Diez I., Contreras M., Vicente J., Cabezas-Cruz A., et al. 2015. Comparative genomics of field isolates of Mycobacterium bovis and M. caprae provides evidence for possible correlates with bacterial viability and virulence. PLoS Neglected Tropical Diseases. 9(11):e0004232.

 

2014

  1. Cabezas-Cruz A., et al. 2014. Cancer research meets tick vectors for infectious diseases. THE LANCET Infectious Diseases. 14(10): 916-917.
  2. Cabezas-Cruz A & Valdés J J. 2014. Are ticks venomous animals? Frontiers in Zoology. 11: 47. Highly accessed! ScienceNewsBlog: https://www.sciencenews.org/blog/wild-things/yet-another-reason-hate-ticks ScienceBlongs: http://scienceblogs.com/lifelines/2014/07/06/venomous-ticks/
  3. Cabezas-Cruz A., et al. 2014. The glycoprotein TRP36 of Ehrlichia sp. UFMG-EV and related cattle pathogen Ehrlichia sp. UFMT-BV evolved from a highly variable clade of E. canis under adaptive diversifying selection. Parasites & Vectors. 7:584.
  4. Cabezas-Cruz A., et al. 2014. Epigenetic control of gene function in schistosomes: a source of therapeutic targets? Frontiers in Genetics. 5:317.
  5. Schwarz A*., Cabezas-Cruz A*., et al. 2014. Understanding the evolutionary structural variability and target specificity of tick salivary peptides using next generation transcriptome data. BMC Evolutionary Biology. 14:4. *Joint first authors.
  6. Zweygarth E., Cabezas-Cruz A., et al. 2014. In vitro culture and structural differences in the major immunoreactive protein gp36 of geographically distant Ehrlichia canis isolates. Ticks and tick-borne diseases. 5(4): 423–431.
  7. Mutshembele A M., Cabezas-Cruz A., et al. 2014. Epidemiology and evolution of genetic variability of Anaplasma marginale in South Africa. Ticks and tick-borne diseases. 5(6): 624-631.
  8. Tonk M., Cabezas-Cruz A., et al. 2014. Identification and partial characterisation of new members of the Ixodes ricinus defensin family. Gene. 540 (2): 146–152.
  9. Silva J B., Cabezas-Cruz A., et al. 2014. Infection of water buffalo in Rio de Janeiro Brazil with Anaplasma marginale strains also reported in cattle. Veterinary Parasitology. 205 (2014): 730–734.
  10. Tonk M., Cabezas-Cruz A., et al. 2014. Defensins from the tick Ixodes scapularis are effective against phytopathogenic fungi and the human bacterial pathogen Listeria grayi. Parasites & Vectors. 7: 554.
  11. Silva J B., Fonseca A H., Barbosa J D., Cabezas-Cruz A., et al. 2014. Low genetic diversity associated with low prevalence of Anaplasma marginale in water buffaloes in Marajó Island, Brazil. Ticks and tick-borne diseases. 5(6): 801-804.

 

2013

  1. Cabezas-Cruz A., et al. 2013. Functional and Immunological Relevance of Anaplasma marginale Major Surface Protein 1a Sequence and Structural Analysis. PLoS ONE. 8(6): e65243.
  2. Cabezas-Cruz A., et al. 2013. Ultrastructure of Ehrlichia mineirensis, a new member of the Ehrlichia genus. Veterinary Microbiology. 167(3–4): 455–458.
  3. Pohl A E., Cabezas-Cruz A., et al. 2013. Detection of genetic diversity of Anaplasma marginale isolates in Minas Gerais, Brazil. Brazilian journal of veterinary parasitology. 22(1):129–135.
  4. Zweygarth E., Schöl H., Lis K., Cabezas-Cruz A., et al. 2013. In vitro culture of a novel genotype of Ehrlichia sp. from Brazil. Transboundary and Emerging Diseases. 60 (Suppl. 2) 86–92.
  5. Preston S G., Majtán J., Kouremenou C., Rysnik O., Burger L F., Cabezas-Cruz A., et al. 2013. Novel immunomodulators from hard ticks selectively reprogramme human dendritic cell responses. PLoS Pathogens. 9(6): e1003450.

 

2012

  1. Cabezas-Cruz A., et al. 2012. New species of Ehrlichia isolated from Rhipicephalus (Boophilus) microplus shows an ortholog of the E. canis major immunogenic glycoprotein gp36 with a new sequence of tandem repeats. Parasites & Vectors. 5: 291.

Publications
Total found: 38 records
Cabezas-Cruz A., Alberdi P., Valdés J. J., Villar J.J., de la Fuente J. (2017) Remodeling of tick cytoskeleton in response to infection with Anaplasma phagocytophilum. Frontiers in Bioscience-Landmark 22 : 1830-1844.
Cabezas-Cruz A., Alberdi P., Valdés J. J., Villar M., de la Fuente J. (2017) Anaplasma phagocytophilum Infection Subverts Carbohydrate Metabolic Pathways in the Tick Vector, Ixodes scapularis Frontiers in Cellular and Infection Microbiology 7 : 23.
DOI: 10.3389/fcimb.2017.00023
Cabezas-Cruz A., Espinosa P.J., Obregón D.A., Albedri P., de la Fuente J. (2017) Ixodes scapularis tick cells control Anaplasma phagocytophilum infection by increasing the synthesis of phosphoenolpyruvate from tyrosine Frontiers in Cellular and Infection Microbiology 7 : 375.
DOI: 10.3389/fcimb.2017.00375
Cabezas-Cruz A., Estrada-Peňa A., Rego R. O. M., de la Fuente J. (2017) Tick-pathogen ensembles: do molecular interactions lead ecological innovation? Frontiers in Cellular and Infection Microbiology 7 : 74.
DOI: 10.3389/fcimb.2017.00074
Cabezas-Cruz A., Mateos-Hernández L., Alberdi P., Villar M., Riveau G., Hermann E., Schacht A.-M., Khalife J., Correia-Neves M., Gortazar C., de la Fuente J. (2017) Effect of blood type on anti-α-Gal immunity and the incidence of infectious disease Experimental and Molecular Medicine 49 : e301.
DOI: 10.1038/emm.2016.164
Cabezas-Cruz A., Mateos-Hernández L., Chmelař J., Villar M., de la Fuente J. (2017) Salivary Prostaglandin E2: Role in Tick-Induced Allergy to Red Meat Trends in Parasitology 33 : 495-498.
DOI: 10.1016/j.pt.2017.03.004
Contreras M., Alberdi P., Mateos-Hernández L., Fernández de Mera I.G., García-Pérez A., Vancová M., Villar M., Ayllón N., Cabezas-Cruz A., Valdés J. J., Stuen S., Gortazar C., de la Fuente J. (2017) Anaplasma phagocytophilum MSP4 and HSP70 Proteins Are Involved in Interactions with Host Cells during Pathogen Infection. Frontiers in Cellular and Infection Microbiology 7 : 307.
DOI: 10.3389/fcimb.2017.00307
de la Fuente J., Antunes S., Bonnet S., Cabezas-Cruz A., Domingos A., Estrada-Peňa A., Johnson N., Kocan K., Mansfield K., Nijhof A., Papa A., Rudenko N., Villar M., Alberdi P., Torina A., Ayllón N., Vancová M., Golovchenko M., Grubhoffer L., Caracappa S., Fooks A., Gortazar C., Rego R. O. M. (2017) Tick-pathogen interactions and vector competence: identification of molecular drivers for tick-borne diseases Frontiers in Cellular and Infection Microbiology 7 : 114.
DOI: 10.3389/fcimb.2017.00114
Estrada-Peňa A., de la Fuente J., Cabezas-Cruz A. (2017) Functional redundancy and ecological innovation shape the circulation of tick-transmitted pathogens. Frontiers in Cellular and Infection Microbiology 7 : 234.
DOI: 10.3389/fcimb.2017.00234
Fernández de Mera I.G., Chaligiannis I., Hernández-Jarguín A., Villar M., Mateos-Hernández L., Papa A., Sotiraki S., Ruiz-Fons F., Cabezas-Cruz A., Gortazar C., de la Fuente J. (2017) Combination of RT-PCR and proteomics for the identification of Crimean-Congo hemorrhagic fever virus in ticks Heliyon 3 : e00353.
DOI: 10.1016/j.heliyon.2017.e00353
Mateos-Hernández L., Villar M., Moral A., Rodríguez C.G., Arias T. A., de la Osa V., Brito F.F., Fernández de Mera I.G., Alberdi P., Ruiz-Fons F., Cabezas-Cruz A., Estrada-Peňa A., de la Fuente J. (2017) Tick-host conflict: immunoglobulin E antibodies to tick proteins in patients with anaphylaxis to tick bite Oncotarget 8 : 20630-20644.
DOI: 10.18632/oncotarget.15243
Cabezas-Cruz A., Alberdi P., Ayllón N., Valdés J. J., Pierce R., Villar M., de la Fuente J. (2016) Anaplasma phagocytophilum increases the levels of histone modifying enzymes to inhibit cell apoptosis and facilitate pathogen infection in the tick vector Ixodes scapularis Epigenetics 11 : 303-319.
DOI: 10.1080/15592294.2016.1163460
Cabezas-Cruz A., Estrada-Peňa A., Valdés J. J., de la Fuente J. (2016) Be aware of ticks when strolling through the park Frontiers for Young Minds 4 : 24.
DOI: 10.3389/frym.2016.00024
Cabezas-Cruz A., Tonk M., Bouchut A., Pierrot C., Pierce R., Kotsyfakis M., Rahnamaeian M., Vilcinskas A., Khalife J., Valdés J. J. (2016) Antiplasmodial activity is an ancient and conserved feature of tick defensins Frontiers in Microbiology 7 : 1682.
DOI: 10.3389/fmicb.2016.01682
Cabezas-Cruz A., Valdés J. J., de la Fuente J. (2016) Control of vector-borne infectious diseases by human immunity against α-Gal Expert review of vaccines 15 : 953-955.
DOI: 10.1080/14760584.2016.1181547
Tellier G., Lenne A., Cailliau-Maggio K., Cabezas-Cruz A., Valdés J. J., Martoriati A., Aliouat E., Gosset P., Delaire B., Fréville A., Pierrot C., Khalife J. (2016) Identification of Plasmodium falciparum Translation Initiation eIF2β Subunit: Direct Interaction with Protein Phosphatase Type 1 Frontiers in Microbiology 7 : 777.
DOI: 10.3389/fmicb.2016.00777
Valdés J. J., Cabezas-Cruz A., Šíma R., Butterill P. T., Růžek D., Nuttall P. (2016) Substrate prediction of Ixodes ricinus salivary lipocalins differentially expressed during Borrelia afzelii infection. Scientific Reports 6 : 32372.
DOI: 10.1038/srep32372
Ayllón N., Naranjo V., Hajdušek O., Villar M., Galindo R., Kocan K., Alberdi P., Šíma R., Cabezas-Cruz A., Rückert C., Bell-Sakyi L., Kazimírová M., Havlíková S., Klempa B., Kopáček P., de la Fuente J. (2015) Nuclease Tudor-SN Is Involved in Tick dsRNA-Mediated RNA Interference and Feeding but Not in Defense against Flaviviral or Anaplasma phagocytophilum Rickettsial Infection PLoS One 10 : e0133038.
DOI: 10.1371/journal.pone.0133038
Ayllón N., Villar M., Galindo R., Kocan K., Šíma R., López J., Vázquez J., Alberdi P., Cabezas-Cruz A., Kopáček P., de la Fuente J. (2015) Systems Biology of Tissue-Specific Response to Anaplasma phagocytophilum Reveals Differentiated Apoptosis in the Tick Vector Ixodes scapularis PLoS Genetics 11 : e1005120.
DOI: 10.1371/journal.pgen.1005120
Cabezas-Cruz A., Mateos-Hernández L., Pérez-Cruz M., Valdés J. J., Mera I., Villar M., de la Fuente J. (2015) Regulation of the Immune Response to α-Gal and Vector-borne Diseases Trends in Parasitology 31 : 470-476.
DOI: 10.1016/j.pt.2015.06.016

More publications

CONTACT

Biology Centre CAS
Institute of Parasitology
Branišovská 1160/31
370 05 České Budějovice

Staff search