MSc. Astrid Sibylle Holzer, Ph.D.

Job Position: Head of Laboratory - Laboratory of Fish Protistology

Contact details

Phone: +420 387775424
E-mail: astrid.holzer@paru.cas.cz
Room: 138

Description

Specialist in aquatic parasitology in aquaculture systems and natural marine and freshwater habitats: morphology, identification, diversity, distribution and ecology, phylogeny and evolution, life cycles, host-parasite relationships, pathology, transmission, transcriptomics and proteomics, functional antiparasitic approaches. Specialization in and passion for myxozoan parasites with current projects focussing on the mechanisms and molecules involved in host-parasite interaction responsible for rapid parasite proliferation and propagation in the host.

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Curriculum vitae

Academic education and employment

  • In 2011 hired as Head of Department of Protistology and Head of Laboratory of Fish Protistology, Institute of Parasitology, Biology Center of the Academy of Sciences of the Czech Republic.
  • 2010 Abroad fellowship (6 months) at the Department of Specific Prophylaxis and Tropical Medicine, Medical University of Vienna, Austria.
  • 2005-2010 Marie Curie Experienced Researcher (2005-2007) and Juan de la Cierva Research Fellow (2008-2010) at the Cavanilles Institute of Biodiversity and Evolutionary Biology, University of Valencia, Spain.
  • 2000-2005 PhD in Aquatic Veterinary Pathology (2000-2004) and research assistant (2004-2005), Institute of Aquaculture, University of Stirling, UK.
  • 1999-2000 Project-associated researcher, Institute of Hydrobiology and Ichthyology (now: Clinic for Avian, Reptiles and Fish), University of Veterinary Medicine of Vienna, Austria.
  • 1992-1999 Combined BSc / MSc in Biology with specialization in Zoology and Marine Biology, University of Vienna, Austria.

Recent projects

  • Turn the tide on limited myxozoan phylogeny: using high throughput sequencing to discover new Myxozoa species from the Southwest Atlantic Ocean. Czech Academy of Sciences/Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET) (#CONICET-16-06; 2017-2018).
  • Testing parasiticidal and immunomodulatory substances to combat myxozoan infections in aquaculture using novel in vitro and in vivo models. Technology Agency of the Czech Republic (#TG02010016; 2016-2018).
  • Large scale fish and water environment screening to assess the biodiversity of the Myxozoa: A metagenomic approach. Czech Science Foundation (#16-20744S; 2016-2018).
  • ParaFishControl - Advanced tools and research strategies for parasite control in European farmed fish. European Commission RIA - Research and Innovation Action, H2020 SFS-2014-2 Sustainable Food Security (#634429, 2015-2020). 
  • ECIP - European Centre for Ichthyoparasitology. Center of Excellence, Czech Science Foundation (#505/12/G112; 2012-2018).
  • MODBIOLIN - Use of model organisms to resolve crucial biological problems on the path to innovations. European Commission, FP7-REGPOT-2012-2013-1 (#316304, 2013-2015).
  • Novel Approaches for comparative study of myxozoan life cycle stages -  Identifying genes as well as cellular components of biological relevance for parasite proliferation. CAS Program for international collaboration (#M200961205; 2012-2014).

 

Publications
Total found: 24 records
Born Torrijos A., Holzer A., Raga J., van Beest G.S., Yoneva A. (2017) Description of embryonic development and ultrastructure in miracidia of Cardiocephaloides longicollis (Digenea, Strigeidae) in relation to active host finding strategy in a marine environment Journal of Morphology 278 : 1137-1148.
DOI: 10.1002/jmor.20700
Patra S., Hartigan A., Morris D., Kodádková A., Holzer A. (2017) Description and experimental transmission of Tetracapsuloides vermiformis n. sp. (Cnidaria: Myxozoa) and guidelines for describing malacosporean species including reinstatement of Buddenbrockia bryozoides n. comb. (syn. Tetracapsula bryozoides). Parasitology 144 : 497-511.
DOI: 10.1017/S0031182016001931
Alama Bermejo G., Jirků M., Kodádková A., Pecková H., Fiala I., Holzer A. (2016) Species complexes and phylogenetic lineages of Hoferellus (Myxozoa, Cnidaria) including revision of the genus: A problematic case for taxonomy Parasites & Vectors 9 : 13.
DOI: 10.1186/s13071-015-1265-8
Born Torrijos A., Poulin R., Perez Del Olmo A., Culurgioni J., Raga J., Holzer A. (2016) An optimised multi-host trematode life cycle: fishery discards enhance trophic parasite transmission to scavenging birds International Journal for Parasitology 46 : 745-753.
DOI: 10.1016/j.ijpara.2016.06.005
Born Torrijos A., Raga J., Holzer A. (2016) Trematode maturation patterns in a migratory snail host: What happens during upshore residency in a Mediterranean lagoon? Parasitology Research 115 : 575-585.
DOI: 10.1007/s00436-015-4774-7
Cantatore D., Irigoitia M., Holzer A., Timi J. (2016) Myxozoans as biological tags for stock identification of the Argentine hake, Merluccius hubbsi (Gadiformes: Merlucciidae) Parasitology 143 : 732-740.
DOI: 10.1017/S0031182016000226
Forte-Gil D., Holzer A., Pecková H., Bartošová-Sojková P., Penalver J., Dolores E., Munoz P. (2016) Molecular and morphological identification of Cardicola (Trematoda: Aporocotylidae) eggs in hatchery-reared and migratory Atlantic bluefin tuna (Thunnus thynnus L.) Aquaculture 450 : 58-66.
DOI: 10.1016/j.aquaculture.2015.06.043
Hartigan A., Estensoro Atienza I., Vancová M., Bílý T., Patra S., Eszterbauer E., Holzer A. (2016) New cell motility model observed in parasitic cnidarian Sphaerospora molnari (Myxozoa:Myxosporea) blood stages in fish Scientific Reports 6 : 39093.
DOI: 10.1038/srep39093
Hartigan A., Wilkinson M., Gower D., Streicher J., Holzer A., Okamura B. (2016) Myxozoan infections of caecilians demonstrate broad host specificity and indicate a link with human activity International Journal for Parasitology 46 : 375-381.
DOI: 10.1016/j.ijpara.2016.02.001
Wünnemann H., Holzer A., Pecková H., Bartošová-Sojková P., Eskens U., Lierz M. (2016) Repatriation of an old fish host as an opportunity for myxozoan parasite diversity: The example of the allis shad, Alosa alosa (Clupeidae), in the Rhine Parasites & Vectors 9 : 505.
DOI: 10.1186/s13071-016-1760-6
Feist S., Morris D., Alama Bermejo G., Holzer A. (2015) Cellular processes in myxozoans Myxozoan Evolution, Ecology and Development, B. Okamura et al. (Eds.) 139-154.
Kodádková A., Bartošová-Sojková P., Holzer A., Fiala I. (2015) Bipteria vetusta n. sp. – an old parasite in an old host: tracing the origin of myxosporean parasitism in vertebrates International Journal for Parasitology 45 : 269-276.
DOI: 10.1016/j.ijpara.2014.12.004
Bartošová-Sojková P., Hrabcová M., Pecková H., Patra S., Kodádková A., Jurajda P., Tyml T., Holzer A. (2014) Hidden diversity and evolutionary trends in malacosporean parasites (Cnidaria: Myxozoa) identified using molecular phylogenetics International journal for parasitology 44 : 565-577.
DOI: 10.1016/j.ijpara.2014.04.005
Born Torrijos A., Holzer A., Raga J., Kostadinova A. (2014) Same host, same lagoon, different transmission pathways: Effects of exogenous factors on larval emergence in two marine digenean parasites Marine Ecology Progress Series 113 : 545-554.
DOI: 10.1007/s00436-013-3686-7
Born Torrijos A., Poulin R., Raga J., Holzer A. (2014) "Estimating trematode prevalence in snail hosts using a single-step duplex PCR: how badly does cercarial shedding underestimate infection rates?" Parasites & Vectors 7 : 243.
DOI: 10.1186/1756-3305-7-243
Holzer A., Hartigan A., Patra S., Pecková H., Eszterbauer E. (2014) Molecular fingerprinting of the myxozoan community in common carp suffering Swim Bladder Inflammation (SBI) identifies multiple etiological agents Parasites & Vectors 7 : 398.
DOI: 10.1186/1756-3305-7-398
Alama Bermejo G., Šíma R., Raga J., Holzer A. (2013) Understanding myxozoan infection dynamics in the sea: Seasonality and transmission of Ceratomyxa puntazzi International Journal for Parasitology 43 : 771-780.
DOI: 10.1016/j.ijpara.2013.05.003
Bartošová P., Fiala I., Cinková M., Jirků M., Caffara M., Fioravanti M., Atkinson S., Bartholomew J., Holzer A. (2013) Sphaerospora sensu stricto: Taxonomy, diversity and evolution of a unique lineage of myxosporeans (Myxozoa) Molecular Phylogenetics and Evolution 68 : 93-105.
DOI: 10.1016/j.ympev.2013.02.026
Eszterbauer E., Sipos D., Forró B., Bartošová P., Holzer A. (2013) Molecular characterization of Sphaerospora molnari (Myxozoa), the agent of gill sphaerosporosis in common carp (Cyprinus carpio carpio) Diseases of Aquatic Organisms 104 : 59-67.
DOI: 10.3354/dao02584
Holzer A., Pecková H., Patra S., Brennan N., Yanes-Roca C., Main K. (2013) Severe glomerular disease in juvenile grey snapper Lutjanus griseus L. in the Gulf of Mexico caused by the myxozoan Sphaerospora motemarini n. sp. International Journal for Parasitology: Parasites and Wildlife 2 : 124-130.
DOI: 10.1016/j.ijppaw.2013.03.003

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CONTACT

Biology Centre CAS
Institute of Parasitology
Branišovská 1160/31
370 05 České Budějovice

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