James Jason Valdés, Ph.D.

Funkce: PostDok - Laboratoř arbovirologie

Kontaktní údaje

Telefon: +420 387775458
E-mail: valdjj@gmail.com
Místnost: 614

Popis

Postdoktorand se věnuje počítačovému modelování protein-proteinových interakcí.  To mu mimo jiné umožňuje předpovědět funkci specifických proteinů klíštěcích slin na základě transkriptomu slinných žláz klíštěte Ixpdes ricinus. Přednáší v rámci Kurzu bioinformatiky na PřF JU a vede diplomové práce studentů. Připravil vlastní kurz Structural and Computational Biology, který bude nabízen studentům PřF JU. Během své účasti na projektu Bioglobe publikoval 5 článků v kvalitních impaktovaných časopisech.

Odborný životopis

Informace v anglické verzi.

Publikace
Celkem nalezeno: 32 záznamů
Cabezas-Cruz A., Alberdi P., Valdés J. J., Villar J.J., de la Fuente J. (2017) Remodeling of tick cytoskeleton in response to infection with Anaplasma phagocytophilum. Frontiers in Bioscience-Landmark 22 : 1830-1844.
Cabezas-Cruz A., Alberdi P., Valdés J. J., Villar M., de la Fuente J. (2017) Anaplasma phagocytophilum Infection Subverts Carbohydrate Metabolic Pathways in the Tick Vector, Ixodes scapularis Frontiers in Cellular and Infection Microbiology 7 : 23.
DOI: 10.3389/fcimb.2017.00023
Contreras M., Alberdi P., Mateos-Hernández L., Fernández de Mera I.G., García-Pérez A., Vancová M., Villar M., Ayllón N., Cabezas-Cruz A., Valdés J. J., Stuen S., Gortazar C., de la Fuente J. (2017) Anaplasma phagocytophilum MSP4 and HSP70 Proteins Are Involved in Interactions with Host Cells during Pathogen Infection. Frontiers in Cellular and Infection Microbiology 7 : 307.
DOI: 10.3389/fcimb.2017.00307
Cabezas-Cruz A., Alberdi P., Ayllón N., Valdés J. J., Pierce R., Villar M., de la Fuente J. (2016) Anaplasma phagocytophilum increases the levels of histone modifying enzymes to inhibit cell apoptosis and facilitate pathogen infection in the tick vector Ixodes scapularis Epigenetics 11 : 303-319.
DOI: 10.1080/15592294.2016.1163460
Cabezas-Cruz A., Estrada-Peňa A., Valdés J. J., de la Fuente J. (2016) Be aware of ticks when strolling through the park Frontiers for Young Minds 4 : 24.
DOI: 10.3389/frym.2016.00024
Cabezas-Cruz A., Tonk M., Bouchut A., Pierrot C., Pierce R., Kotsyfakis M., Rahnamaeian M., Vilcinskas A., Khalife J., Valdés J. J. (2016) Antiplasmodial activity is an ancient and conserved feature of tick defensins Frontiers in Microbiology 7 : 1682.
DOI: 10.3389/fmicb.2016.01682
Cabezas-Cruz A., Valdés J. J., de la Fuente J. (2016) Control of vector-borne infectious diseases by human immunity against α-Gal Expert review of vaccines 15 : 953-955.
DOI: 10.1080/14760584.2016.1181547
Tellier G., Lenne A., Cailliau-Maggio K., Cabezas-Cruz A., Valdés J. J., Martoriati A., Aliouat E., Gosset P., Delaire B., Fréville A., Pierrot C., Khalife J. (2016) Identification of Plasmodium falciparum Translation Initiation eIF2β Subunit: Direct Interaction with Protein Phosphatase Type 1 Frontiers in Microbiology 7 : 777.
DOI: 10.3389/fmicb.2016.00777
Valdés J. J., Cabezas-Cruz A., Šíma R., Butterill P. T., Růžek D., Nuttall P. (2016) Substrate prediction of Ixodes ricinus salivary lipocalins differentially expressed during Borrelia afzelii infection. Scientific Reports 6 : 32372.
DOI: 10.1038/srep32372
Valdés J. J., Gil V., Butterill P. T., Růžek D. (2016) An all-atom, active site exploration of antiviral drugs that target Flaviviridae polymerases. Journal of General Virology 97 : 2552-2565.
DOI: 10.1099/jgv.0.000569
Cabezas-Cruz A., Mateos-Hernández L., Pérez-Cruz M., Valdés J. J., Mera I., Villar M., de la Fuente J. (2015) Regulation of the Immune Response to α-Gal and Vector-borne Diseases Trends in Parasitology 31 : 470-476.
DOI: 10.1016/j.pt.2015.06.016
Cabezas-Cruz A., Valdés J. J., Lancelot J., Pierce R. (2015) Fast evolutionary rates associated with functional loss in class I glucose transporters of Schistosoma mansoni BMC Genomics 16 : 980.
DOI: 10.1186/s12864-015-2144-6
Eyer L., Valdés J. J., Gil V., Nencka R., Hřebabecký H., Šála M., Salát J., Černý J., Palus M., De Clercq E., Růžek D. (2015) Nucleoside inhibitors of tick-borne encephalitis virus Antimicrobial Agents and Chemotherapy 59 : 5483-5493.
DOI: 10.1128/AAC.00807-15
Formanová P., Černý J., Bolfíková B., Valdés J. J., Kozlova I., Dzhioev Y., Růžek D. (2015) Full genome sequences and molecular characterization of tick-borne encephalitis virus strains isolated from human patients Ticks and Tick-borne Diseases 6 : 38-46.
DOI: 10.1016/j.ttbdis.2014.09.002
Pinheiro-Silva R., Borges L., Coelho L., Cabezas-Cruz A., Valdés J. J., Do Rosário V., de la Fuente J., Domingos A. (2015) Gene expression changes in the salivary glands of Anopheles coluzzii elicited by Plasmodium berghei infection Parasites & Vectors 8 : 485.
DOI: 10.1186/s13071-015-1079-8
Tonk M., Cabezas-Cruz A., Valdés J. J., Grubhoffer L., Rego R. O. M., Estrada-Peňa A., Vilcinskas A., Kotsyfakis M., Rahnamaeian M. (2015) Ixodes ricinus defensins attack distantly-related pathogens Developmental & Comparative Immunology 53 : 358-365.
DOI: 10.1016/j.dci.2015.08.001
Tonk M., Knorr E., Cabezas-Cruz A., Valdés J. J., Kollewe C., Vilcinskas A. (2015) Tribolium castaneum defensins are primarily active against Gram-positive bacteria Journal of Invertebrate Pathology 132 : 208-215.
DOI: 10.1016/j.jip.2015.10.009
Cabezas-Cruz A., Valdés J. J. (2014) Are ticks venomous animals? Frontiers in Zoology 11 : 47.
DOI: 10.1186/1742-9994-11-47
Cabezas-Cruz A., Valdés J. J., de la Fuente J. (2014) Cancer research meets tick vectors for infectious diseases Lancet Infectious Diseases 14 : 916-917.
DOI: 10.1016/S1473-3099(14)70902-8
Cabezas-Cruz A., Valdés J. J., de la Fuente J. (2014) The glycoprotein TRP36 of Ehrlichia sp. UFMG-EV and related cattle pathogen Ehrlichia sp. UFMT-BV evolved from a highly variable clade of E. canis under adaptive diversifying selection Parasites & Vectors 7 : 584.
DOI: 10.1186/s13071-014-0584-5

Více publikací

KONTAKT

Biologické centrum AV ČR, v.v.i.
Parazitologický ústav
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370 05 České Budějovice

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