Other

Other

Past and ongoing research projects related to:

I. Tick Innate Immunity

1997-1999 Immune system of a tick: Identification and characterization of proteins involved in clotting and melanization of tick hemolymph (A6022701, Grant Agency, Academy Sciences CR, P.I. -P. Kopáček)
2000-2002 Humoral factors and cellular events involved in pathogen transmission by ticks (206/00/266 Grant Agency CR, P.I. - P. Kopáček)
2003-2005 Immune reactions within the gut of the soft tick Ornithodoros moubata (A6022307 Grant Agency, Academy Sciences CR, P.I. - P. Kopáček)
2005-2008 The role of ?2-macroglobulin in pathogen transmission by the tick Ixodes ricinus (IAA600220603, Grant Agency, Academy Sciences CR, P.I. - P. Kopáček).
2010-2012 Functional genomics of the complement-like molecules in the tick Ixodes ricinus (P506/10/2136 Grant Agency CR, P.I. - P. Kopáček)
2015-2017 Interaction of the tick complement system with Borrelia and Babesia (15-12006Y Grant Agency CR, P.I. - V. Urbanová)

II. Tick gut, iron metabolism and blood digestion

2005-2008 Peptidases in the gut of the hard tick Ixodes ricinus: characterization and potential for vector-control (206/060/865, Grant Agency CR, P.I. – P. Kopáček)
2009-2011 Hemoglobinolytic aspartic peptidase IrCD - a member of the gut-associated digestive enzyme complex in the tick I. ricinus(KJB600960911, Grant Agency, Academy Sciences CR, P.I. - D. Sojka)
2009-2012 The digestive system of ticks – the target for rational development of vaccine against tick and tick-borne pathogens (IAA600960910 Grant Agency, Academy Sciences CR, P.I. –P. Kopáček)
2010-2013 Structural Proteomics of proteolytic system in ticks (P207/10/2183, Grant Agency CR, P.I. – M. Mareš, IOCB, ASCR, Prague; co-P.I. – P. Kopáček)
2013-2017  The role of hemoglobin in tick metabolism and transmission of tick-borne pathogens (13-11043S, Grant Agency CR, P.I. - P. Kopáček)  
2014-2016 Multiple tick legumains in blood processing, innate immunity and pathogen transmission  (P502/ 14-33693S Grant agency CR, P.I. - D. Sojka)

 

7FP EU ANTIDotE (2014-2018) Anti-tick vaccines to prevent tick-borne diseases in Europe

ANTIDotE (ANti-tick vaccines to prevent TIck-borne Diseases in Europe) is an international research consortium that aims to identify and develop novel ways to prevent multiple human tick-borne diseases in Europe. 

http://www.antidote-fp7.org/

 
 

US patent:
United States Patent  Patent No.: US 8,168,763 B2  .  Date of Patent: May 1, 2012

FERRITIN 2 FOR THE HOST IMMUNIZATION AGAINST TICKS
 
Inventors: 
Petr Kopacek,  Ondrej Hajdusek 

CONTACT

Biology Centre CAS
Institute of Parasitology
Branišovská 1160/31
370 05 České Budějovice

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