Past and ongoing research projects related to:
I. Tick Innate Immunity
2000-2002 Humoral factors and cellular events involved in pathogen transmission by ticks (206/00/266 Grant Agency CR, P.I. - P. Kopáček)
2003-2005 Immune reactions within the gut of the soft tick Ornithodoros moubata (A6022307 Grant Agency, Academy Sciences CR, P.I. - P. Kopáček)
2005-2008 The role of ?2-macroglobulin in pathogen transmission by the tick Ixodes ricinus (IAA600220603, Grant Agency, Academy Sciences CR, P.I. - P. Kopáček).
2010-2012 Functional genomics of the complement-like molecules in the tick Ixodes ricinus (P506/10/2136 Grant Agency CR, P.I. - P. Kopáček)
II. Tick gut, iron metabolism and blood digestion
2009-2011 Hemoglobinolytic aspartic peptidase IrCD - a member of the gut-associated digestive enzyme complex in the tick I. ricinus(KJB600960911, Grant Agency, Academy Sciences CR, P.I. - D. Sojka)
2009-2012 The digestive system of ticks – the target for rational development of vaccine against tick and tick-borne pathogens (IAA600960910 Grant Agency, Academy Sciences CR, P.I. –P. Kopáček)
2010-2013 Structural Proteomics of proteolytic system in ticks (P207/10/2183, Grant Agency CR, P.I. – M. Mareš, IOCB, ASCR, Prague; co-P.I. – P. Kopáček)
7FP EU ANTIDotE (2014-2018) Anti-tick vaccines to prevent tick-borne diseases in Europe
ANTIDotE (ANti-tick vaccines to prevent TIck-borne Diseases in Europe) is an international research consortium that aims to identify and develop novel ways to prevent multiple human tick-borne diseases in Europe.
United States Patent Patent No.: US 8,168,763 B2 . Date of Patent: May 1, 2012
FERRITIN 2 FOR THE HOST IMMUNIZATION AGAINST TICKS
Petr Kopacek, Ondrej Hajdusek