Mgr. Hynek Mazanec, PhD.

Job Position: PhD student - Laboratory of Helminthology

Contact details

Phone: +420 387775167
E-mail: hynek.mazanec@paru.cas.cz
Web: www.researchgate.net/profile/Hynek-Mazanec
Room: 212

Description

Junior postdoc, currently with focus on extracellular vesicles and ultrastructure of tapeworms.

Curriculum vitae

Education:

• PhD / University of South Bohemia Budweiss

Since July 2018 to April 2023
Degree in Parasitology
PhD Thesis: Isolation and characterisation of extracellular vesicles of parasitic helminths (in English)

• Master / University of South Bohemia Budweis

From September 2015 to June 2018
Degree in Parasitology
Master thesis: Molecular and morphological characterisation of digeneans of the family Strigeidae Railliet, 1919 from Iceland (in English)

• Bachelor / University of Hradec Králové Hradec Králové

From September 2012 to June 2015
Degree in Systematic Biology and Ecology
Bachelor thesis: Monitoring of activity of bats in different ecosystems (in Czech)

Recent publications:

• Mazanec, H., Koník, P., Gardian, Z., Kuchta, R. (2021). Extracellular vesicles secreted by model tapeworm Hymenolepis diminuta: Biogenesis, ultrastructure and protein composition. International Journal for Parasitology, 51, 327–332. 
• Mazanec, H., Bušková N., Gardian, Z.,  Kuchta, R. (2023). Secretion of extracellular vesicles during ontogeny of the tapeworm Schistocephalus solidus. Folia Parasitologica, 70:003. 
• White, R., Sotillo, J., Ancarola, M. E., Borup, A., Boysen, A. T., Brindley, P. J., Buzás, E. I., Cavallero, S., Chaiyadet, S., Chalmers, I. W., Cucher M. A., Dagenais, M., Davis, C. N., Devaney, E., Duque-Correa, M. A., Eichenberger R. M., Fontenla S., Gasan, T. A., Hokke, C. H., Kosanovic, M., Kuipers, M. E., Laha, T., Loukas A., Maizels, R. M., Marcilla, A., Mazanec, H., Morphew, R. M., Neophytou, K., Nguyen, L. T., Hoen, E. N., Povelones, M., Robinson, M. W., Rojas, A., Schabussova, I., Smits, H. H., Sungpradit, S., Tritten, L., Whitehead, B., Zakeri A., Nejsum, P., Buck, A. H., Hoffmann K. F. (2023). Special considerations for studies of extracellular vesicles from parasitic helminths: A community-led roadmap to increase rigor and reproducibility. Journal of Extracellular Vesicles, 12(1), 12298. 

Conferences:

• Mazanec, H., Roháčová, J., Georgieva, S., Faltýnková, A. (2016). Molecular and morphological characterisation of larval and adult isolates of digeneans of the family Strigeidae Railliet, 1919 from Iceland. XII. Czech and Slovak Parasitological Days, poster.
• Mazanec, H., Cifre, S., Gozalbo, M., Galiano, A., Domingo, E., Marcilla, A., Köster, P., Carmena, D., Trelis, M. (2017). First report of Blastocystis sp. in rural children of Soavinarivo (Madagascar). II Congreso Nacional de jóvenes investigadores en Biomedicina e IDT, poster.
• Mazanec, H. (2018). Digeneans of the family Strigeidae Railliet, 1919 from Iceland: morphology and molecular characterisation.  24th Helminthological days, talk.
• Mazanec, H. (2019). Extracellular vesicles: From “trash“ to intercellular communicators.  25th Helminthological days, talk.
• Trelis, M., Domingo, E., Mazanec, H., Cifre, S., Gozalbo, M., Galiano, A., Tapia, E., Köster, P., Carmena, D. (2019). Frecuencia y diversidad de subtipos de Blastocystis sp. en población infantil rural (Soavinarivo, Madagascar). III Congreso Conjunto de SEICV y SVAMC, poster.
• Bušková, N., Kuchta, R., Mazanec, H. (2021). Extracellular vesicles during the ontogeny of the tapeworm Schistocephalus solidus. 26th Helminthological days, poster.
• Mazanec, H. (2021). Diversity and role of extracellular vesicles in the host-parasite crosstalk. 20th international conference on diseases of fish and shellfish, invited talk.
• Mazanec, H. (2022). Biogenesis machineries behind "chain-forming" nanotubes and their subsequent dissociation into extracellular vesicles (cEVs) in distinct tapeworm species. XIV. Czech and Slovak Parasitological Days, poster.

Workshops:
2017: CEEPUS on Biota Research II, Poznan, Poland.
2019: Extracellular vesicles in Biomedicine, Valencia, Spain.
2022: Biological specimens in electron microscopy, Budweis, Czechia.
Abroad stays:
2017 (Sep – Dec): Facultat de Farmacia, Universitat de Valencia, Valencia, Spain
2021 (June – July): Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid,  Spain
2021 (Sep – Oct): Institute of Parasitology, University of Zürich, Zürich, Switzerland.

Pedagogical activities:
2020 (Dec) – 2022 (Jan): Bušková, N. Occurrence of extracellular vesicles during the life-cycle of tapeworm Schistocephalus solidus. Supervision of bachelor thesis. Faculty of Sciences, University of South Bohemia, Czech Republic.
2019 – 2020: Biology of helminths (KPA/484). Teaching assistant. Faculty of Sciences, University of South Bohemia, Czech Republic.
2020 – 2023: Biological laboratory technique (KBO/004). Teaching assistant. Faculty of Sciences, University of South Bohemia, Czech Republic.

Other:
2018 (Aug) – 2023 (Jan): Academic senator (Faculty). Faculty of Sciences, University of South Bohemia, Czech Republic.
2020 (Nov) – 2023 (Jan): Academic senator (University). University of South Bohemia, Czech Republic.

 

Publications