Institute of Parasitology invites you to the seminar: “Insights into pathogenesis of diseases accompanying suppressed HIV-1 infection” The seminar will be held at 13:00 on Wednesday 4 October 2023 in seminar room PARU II (2nd floor PARU Animal Facility), Institute of Parasitology Abstract: Anti-retroviral therapy (ART)...
Malaria, an infectious disease caused by parasites belonging to the Plasmodium genus and transmitted by infected mosquitoes, is responsible for mortality and morbidity in over 40% of the world, making it one of the most devastating diseases in human history. In fact, the disease is thought to be responsible for between 2-5% of all fatalities that occurred during the 20th century (between 150...
The predoctoral contract (FPI fellowship) associated with the research project Evolutionary and ecological determinants of specialization: Disentangling the drivers of host specificity in a fishmonogenean model. funded by the Ministry of Science and Innovation of Spain.
Serial block-face scanning electron microscopy (SBF-SEM or SBEM) is a state-of-the-art groundbreaking technique that offers volume imaging of ~1 mm3 large biological objects at nanometer-scale resolution. We have successfully applied the minimal resin (MR) embedding method to the sample preparation protocol and showed that this simple approach tackles simultaneously two major problems of...
Summary We have generated a high-confidence mitochondrial proteome (MitoTag) of the Trypanosoma brucei procyclic stage containing 1,239 proteins. For 337 of these, a mitochondrial localization had not been described before. We use the TrypTag dataset as a foundation and take advantage of the properties of the fluorescent protein tag that causes...
Wu-Chuang A., Mateos-Hernandez L., Maitre A., Rego R.O.M., Šíma R. , Porcelli S., Rakotobe S., Foucault-Simonin A., Moutailler S., Palinauskas V., Aželytė J., Šimo L., Obregon D., Cabezas-Cruz A. 2023: Microbiota perturbation by anti-microbiota vaccine reduces the colonization of Borrelia afzelii in Ixodes ricinus. Microbiome 11: 151. [IF=15.500] DOI: 10.1186/s40168-023-01599-7...
Summary Mechanistic studies on how eukaryotes ensure vertical inheritance of beneficial intracellular prokaryotes have focused mostly on highly integrated relationships. A new study by Zakharova, Tashyreva et al. reveals how a duplicated host gene impacts symbiont inheritance in a young mutualism. Main text Symbiotic relationships between...
Lyme disease (Lyme borreliosis) is a tick-borne bacterial infection that occurs in the temperate climates of North America and Eurasia. Treatment with antibiotics is effective only in the early stages of infection. Although the first human Lyme disease vaccine (LYMErix by SmithKline Beecham, Pittsburgh, PA, USA) was marketed and distributed in the USA from 1998 until 2002, it was discontinued...
