Engineered Plasmodium parasites form the basis of two experimental malaria vaccines that showed safety and encouraging immune responses in clinical trials. by Ruth Williams
More K., Klinger C.M., Barlow L.D., Dacks J.B. 2020: Evolution and natural history of membrane trafficking. Current Biology 30: R553–R564.
Pánek T., Eliáš M., Vancová M., Lukeš J., Hashimi H. 2020: Returning to the fold for lessons in mitochondrial crista diversity and evolution. Current Biology 30: R575–R588
Genetic tool development in marine protists: emerging model organisms for experimental cell biology Abstract Diverse microbial ecosystems underpin life in the sea. Among these microbes are many unicellular eukaryotes that span the diversity of the eukaryotic tree of life. However, genetic tractability has been limited to a few species, which do not represent eukaryotic...
Molecular parasitologist Zdeněk Paris successfully cured from Covid-19. He returns to work to help colleagues with testing the clinical samples on this disease.
Genetic tool development in marine protists: emerging model organisms for experimental cell biology Abstract Diverse microbial ecosystems underpin life in the sea. Among these microbes are many unicellular eukaryotes that span the diversity of the eukaryotic tree of life. However, genetic tractability has been limited to a few species, which do not represent eukaryotic diversity...
The overlooked marine single-celled protists, which have a major impact on life on the planet, has now received greater scientific attention. One hundred and thirteen scientists from 53 laboratories from 14 countries around the world have united forces to develop genetic methods to investigate these microscopic organisms, taking ocean research a step further.
Coronaviruses (CoVs) traffic frequently between species resulting in novel disease outbreaks, most recently exemplified by the newly emerged SARS-CoV-2. Herein, we show that the ribonucleoside analog β-D-N4-hydroxycytidine (NHC, EIDD-1931) has broad spectrum antiviral activity against SARS-CoV 2, MERS-CoV, SARS-CoV, and related zoonotic group 2b or 2c Bat-CoVs, as well as increased potency...
Dr. Klara Petrzelkova from the Institute of Vertebrate Biology and the Institute of Parasitology, Biology Centre, participated in an expedition to Central Africa with the aim to understand the microbiome of the hunter-gatherers. The HBO video has a quatre million views within a month".
Highlights Unrelated bacterial symbionts from marine diplonemids show convergent evolution The symbionts have reduced genomes with similar content and metabolic potential The symbionts contain secretion systems including the type secretion system Diverse symbionts from a large range of eukaryotic hosts have similar modified cellular machinery...