prof. Ing. Martin Kváč, Ph.D.

Job Position: Head of Laboratory - Laboratory of Veterinary and Medical Protistology

Contact details

Phone: +420 387775419
E-mail: kvac@paru.cas.cz
Room: 113

Description

Research interests

  • Endoparasites of farm and wild animals, including infectivity, pathogenity and relation to hosts.

 

Research priorities

Opportunistic protozoa, especially Cryptosporidia, Microsporidia and Giardia

Curriculum vitae

Education and professional experience

  • 1999: MSc. at the Faculty of Agriculture, University of South Bohemia České Budějovice.

  • 2003: Ph.D. at the Faculty of Agriculture, University of South Bohemia České Budějovice
  • 2003: research assistant at Institute of Parasitology ASCR, České Budějovice
  • 2004: assistant of professor at Faculty of Agriculture, University of South Bohemia České Budějovice
  • 2004: research scientist at Institute of Parasitology ASCR, České Budějovice
  • 2009: associated professor at Faculty of Agriculture, University of South Bohemia České Budějovice
  • 2009: head of Laboratory of Veterinary and Medical Protistology, Institute of Parasitology ASCR, České Budějovice

 

Grant projects

  • Occurence of microsporidia on the pig farms (2007)
  • Immune response of mice to infection with different gastric cryptosporidia from mammals (2007-2009)
  • Zoonotic potencial of Cryptosporidium species infecting cattle and pigs (2007-2009)
  • Host specifity and morphological variability of pig cryptosporidia (2006)
  • Gastric cryptosporidia in mammals: variability and host specificity (2005-2007)
  • Impact of increased contact with humans on diversity and ecology of protozoan parasites of African great apes (2009-2011) 
  • Prevalence, genotypic characterization and clinical effects caused by Blastocystis hominisi n patients with HIV and AIDS (2010-2012)
  • Use of genetic and biotechnological methods for improving the health of animals (2010-2012) 
  • Diversity, biology and phylogeny of Cryptosporidium spp. parasiting in rodents (2011-2014)
  • Anti-inflammatory activity of extracts isolated from selected Indonesian plants and their effect on opportunistic parasitoses (2011-2015)
  • Development of scientific team and laboratory for infectious diseases common to humans and great apes (2012-2015)
  • Livestock health and food safety - genetic, parasitic and nutritional aspects (2013-2015) 
  • Clinical, immunological and molecular profile of microsporidiosis and cryptosporidiosis in patients living with HIV in the population of Lower Silesia (2013-2014)
  • The application of molecular methods to identify and characterize Microsporidia in immunocompetent and immunosuppressed patients with kidney disease and evaluating the impact of selected drugs on the process of Microsporidia invasion in in vitro research (2013-2017)
  • Revealing Cryptosporidium diversity: Linking genetic variation to parasite biology (2015-2017)

 

Stays abroad

  • Universität für Bodenkultur Wien, Austria (2000)
  • Institut für Parasitologie und Zoologie, Veterinärmedizinische Universität Wien, Austria (2000)
  • Centers for Diseases Control and Prevention, Division of Parasitic Diseases, Atlanta, Georgia USA (2007)
  • Centers for Diseases Control and Prevention, Division of Parasitic Diseases, Atlanta, Georgia USA (2008)
  • Wroclaw Medical University, Department of Biology and Medical Parasitology, Wrocław, Poland (2009)
  • Center for Food Safety, College of Agricultural and Environmental Sciences, Griffin, Georgia, USA  (2011)
  • North Dakota State University, Department of Veterinary and Microbiological Sciences, North Dakota, USA (2011)
  • North Dakota State University, Department of Veterinary and Microbiological Sciences, North Dakota, USA (2012)
  • North Dakota State University, Department of Veterinary and Microbiological Sciences, North Dakota, USA (2014)
  • University of Ottawa, Department of Biology, Ottawa Canada (2015)

 

Teaching Animal Health Protection
Faculty of Agriculture, University of South Bohemia

Veterinary Parasitology
Faculty of Agriculture, University of South Bohemia

Hygiene and Prevention of Diseases in Farm Animals
Faculty of Agriculture, University of South Bohemia

Publications
Total found: 139 records
He X., Huang W., Sun L., Hou T., Wan Z., Li N., Guo Y., Kváč M., Xiao L., Feng Y. (2022) A productive immunocompetent mouse model of cryptosporidiosis with long oocyst shedding duration for immunological studies Journal of Infection 84 : 710–721.
DOI: 10.1016/j.jinf.2022.02.019
Hoque S., Mavrides D.E., Pinto P. , Costas S. , Begum N., Azevedo-Ribeiro C., Liapi M., Kváč M., Malas S., Gentekaki E., Tsaousis A. (2022) High Occurrence of Zoonotic Subtypes of Cryptosporidium parvum in Cypriot Dairy Farms Microorganisms 10 : 531.
DOI: 10.3390/microorganisms10030531
Kicia M., Zajączkowska Ž., Kváč M., Cebulski K., Holubová N., Wencel P., Mayer L., Wesołowska M., Sak B. (2022) Encephalitozoon cuniculi and Extraintestinal Microsporidiosis in Bird Owners Emerging Infectious Diseases 27 : 3.
DOI: 10.3201/eid2803.211556
Pinto P. , Ribeiro C.A., Kváč M., Tsaousis A. (2022) Cryptosporidium In: W. de Souza (Ed.), Lifecycles of Pathogenic Protists in Humans, Microbiology Monographs series - Volume 35 617 : 331-389.
DOI: 10.1007/978-3-030-80682-8_7
Sak B., Holubová N., Květoňová D., Hlásková L., Tinavská J., Kicia M., Zajączkowska Ž., Kváč M. (2022) Comparison of the Concentration of Encephalitozoon cuniculi Genotypes I and III in Inflammatory Foci Under Experimental Conditions Journal of Inflammation Research 15 : 2721–2730.
DOI: 10.2147/JIR.S363509
Chen J., Wang W., Lin N., Guo Y., Kváč M., Ryan U., Feng Y., Xiao L. (2021) Genetic characterizations of Cryptosporidium spp. from pet rodents indicate high zoonotic potential of pathogens from chinchillas One Health 13 : 100269.
DOI: 10.1016/j.onehlt.2021.100269
Cibot M., McLennan M., Kváč M., Sak B., Asiimwe C., Petrželková K. J. (2021) Sparse Evidence for Giardia intestinalis, Cryptosporidium spp. and Microsporidia Infections in Humans, Domesticated Animals and Wild Nonhuman Primates Sharing a Farm–Forest Mosaic Landscape in Western Uganda Pathogens 10 : 933.
DOI: 10.3390/pathogens10080933
Ježková J., Limpouchová Z., Prediger J., Holubová N., Sak B., Konečný R., Květoňová D., Hlásková L., Rost M., McEvoy J., Rajský D., Feng Y., Kváč M. (2021) Cryptosporidium myocastoris n. sp. (Apicomplexa: Cryptosporidiidae), the Species Adapted to the Nutria (Myocastor coypus) Microorganisms 9 : 813.
DOI: 10.3390/microorganisms9040813
Ježková J., Prediger J., Holubová N., Sak B., Konečný R., Feng Y., Xiao L., Rost M., McEvoy J., Kváč M. (2021) Cryptosporidium ratti n. sp. (Apicomplexa: Cryptosporidiidae) and genetic diversity of Cryptosporidium spp. in brown rats (Rattus norvegicus) in the Czech Republic. Parasitology 148 : 84-97.
DOI: 10.1017/S0031182020001833
Kváč M., Myšková E., Holubová N., Kellnerová K., Kicia M., Rajský D., McEvoy J., Feng Y., Hanzal V., Sak B. (2021) Occurrence and genetic diversity of Cryptosporidium spp. in wild foxes, wolves, jackals, and bears in central Europe Folia Parasitologica 68 : 2.
DOI: 10.14411/fp.2021.002
Myšková E., Brož M., Kváč M., Sak B., Ditrich O. (2021) Intestinal parasites of dogs (Canis lupus familiaris) in Svalbard (Norway): low prevalence and limited transmission with wildlife Canadian Journal of Zoology 99 : 249–255.
DOI: 10.1139/cjz-2020-0186
Pinto P. , Ribeiro C., Hoque S., Hammouma O., Leruste H., Détriché S., Canniere E., Daandels Y., Dellevoet M., Roemen J., Barbier Bourgeois A., Kváč M., Follet J., Tsaousis A. (2021) Cross-Border Investigations on the Prevalence and Transmission Dynamics of Cryptosporidium Species in Dairy Cattle Farms in Western Mainland Europe Microorganisms 9 : 2394.
DOI: 10.3390/microorganisms9112394
Prediger J., Ježková J., Holubová N., Sak B., Konečný R., Rost M., McEvoy J., Rajský D., Kváč M. (2021) Cryptosporidium sciurinum n. sp. (Apicomplexa: Cryptosporidiidae) in Eurasian Red Squirrels (Sciurus vulgaris) Microorganisms 9 : 2050.
DOI: 10.3390/microorganisms9102050
Sak B., Brdíčková K., Holubová N., Květoňová D., Hlásková L., Kváč M. (2021) The course of infection of Encephalitozoon cuniculi genotype I in mice possess combination of features reported in genotypes II and III Experimental Parasitology 224 : 108101.
DOI: 10.1016/j.exppara.2021.108101
Vecková T., Sak B., Samková E., Holubová N., Kicia M., Zajączkowska Ž., Hlásková L., Květoňová D., Kváč M. (2021) Raw Goat's Milk, Fresh and Soft Cheeses as a Potential Source of Encephalitozoon cuniculi Foodborne Pathogens and Disease 18 : 9.
DOI: 10.1089/fpd.2021.0017
Zajączkowska Ž., Akutko K., Kváč M., Sak B., Szydłowicz M., Hendrich A.B., Iwańczak B., Kicia M. (2021) Enterocytozoon bieneusi infects children with inflammatory bowel disease undergoing immunosuppressive treatment Frontiers in Medicine 8 : 741751.
DOI: 10.3389/fmed.2021.741751
Brdíčková K., Sak B., Holubová N., Květoňová D., Hlásková L., Kicia M., Kopacz Ž., Kváč M. (2020) Encephalitozoon cuniculi Genotype II Concentrates in Inflammation Foci. Journal of Inflammation Research 13 : 583–593.
DOI: 10.2147/JIR.S271628
Brdíčková K., Sak B., Holubová N., Květoňová D., Hlásková L., Kicia M., Kopacz Ž., Kváč M. (2020) Encephalitozoon cuniculi genotype II concentrates in inflammation foci Journal of Inflammation Research 13 : 583–593.
DOI: 10.2147/JIR.S271628
Holubová N., Sak B., Schulzová T., Konečný R., Rost M., Tůmová L., McEvoy J., Kváč M. (2020) A chicken embryo model for the maintenance and amplification of Cryptosporidium parvum and Cryptosporidium baileyi oocysts European Journal of Protistology 75 : 125718.
DOI: 10.1016/j.ejop.2020.125718
Holubová N., Tůmová L., Sak B., Hejzlarová A., Konečný R., McEvoy J., Kváč M. (2020) Description of Cryptosporidium ornithophilus n. sp. (Apicomplexa: Cryptosporidiidae) in farmed ostriches Parasites & Vectors 13 : 340.
DOI: 10.1186/s13071-020-04191-2

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CONTACT

Biology Centre CAS
Institute of Parasitology
Branišovská 1160/31
370 05 České Budějovice

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