Doc. Hassan Hashimi, Ph.D.

Funkce: Vědecký pracovník - Laboratoř molekulární biologie prvoků

Kontaktní údaje

Telefon: +420 387775481
E-mail: hassan@paru.cas.cz
Místnost: 1. patro zvěřinec

Odborný životopis

Education:

  • University of Massachusetts at Amherst. B.Sc. Biochemistry and Molecular Biology, 1995, Magna cum laude.
  • The Faculty of Biology, University of South Bohemia, České Budějovice. Mgr. Cell and Developmental Biology, 2005, Červený dipom (with honors).
  • The Faculty of Science, University of South Bohemia, České Budějovice. PhD. Molecular Biology and Biochemistry, 2009.

Výuka Bioenergetics (for Biological Chemistry)
Přírodovědecká fakulta Jihočeské univerzity

Buněčné regulace a signalizace
Přírodovědecká fakulta Jihočeské univerzity

Cell Regulation and Signaling (for Biological Chemistry)
Přírodovědecká fakulta Jihočeské univerzity

Publikace
Celkem nalezeno: 23 záznamů
Benz C., Stříbrná E., Hashimi H., Lukeš J. (2017) Dynamin-like proteins in Trypanosoma brucei: A division of labour between two paralogs? PLoS ONE 12 : e0177200.
DOI: 10.1371/journal.pone.0177200

Dokumenty ke stažení:
Benz et al. 2017 PLoS ONE (pdf)
Dixit S., Müller-McNicoll M., David V., Zarnack K., Ule J., Hashimi H., Lukeš J. (2017) Differential Binding of Mitochondrial Transcripts by MRB8170 and MRB4160 Regulates Distinct Editing Fates of Mitochondrial mRNA in Trypanosomes mBio 8 : e02288-16.
DOI: 10.1128/mBio.02288-16

Dokumenty ke stažení:
Dixit et al. 2017 mBio (pdf)
Hashimi H., Kaltenbrunner S., Zíková A., Lukeš J. (2016) Trypanosome Mitochondrial Translation and Tetracycline: No Sweat about Tet PLoS Pathogens 12 : e1005492.
DOI: 10.1371/journal.ppat.1005492

Dokumenty ke stažení:
Hashimi et al. 2016 PLoS Pathog (pdf)
Read L., Lukeš J., Hashimi H. (2016) Trypanosome RNA editing: the complexity of getting U in and taking U out. Wiley Interdiscip Reviews RNA 7 : 33-51.
DOI: 10.1002/wrna.1313

Dokumenty ke stažení:
Read et al. 2016 WIREs RNA (pdf)
David V., Flegontov P., Gerasimov E., Tanifuji G., Hashimi H., Logacheva M., Maruyama S., Onodera N., Gray M., Archibald J., Lukeš J. (2015) Gene loss and error-prone RNA editing in the mitochondrion of Perkinsela, an endosymbiotic kinetoplastid mBio 6 : e01498-15.
DOI: 10.1128/mBio.01498-15

Dokumenty ke stažení:
David et al 2015 mBio (pdf)
Huang Z., Faktorová D., Křížová A., Kafková L., Read L., Lukeš J., Hashimi H. (2015) Integrity of the core mitochondrial RNA-binding complex 1 is vital for trypanosome RNA editing RNA 21 : 2088-2102.
DOI: 10.1261/rna.052340.115

Dokumenty ke stažení:
Huang et al 2015 RNA (pdf)
Verner Z., Basu S., Benz C., Dixit S., Dobáková E., Faktorová D., Hashimi H., Horáková E., Huang Z., Paris Z., Pena P., Ridlon L., Týč J., Wildridge D., Zíková A., Lukeš J. (2015) The malleable mitochondrion of Trypanosoma brucei Internation Review of Cell and Molecular Biology 315 : 73-151.
DOI: 10.1016/bs.ircmb.2014.11.001

Dokumenty ke stažení:
Verner-IRCMB-2015 (pdf)
Huang Z., Kaltenbrunner S., Šimková E., Staněk D., Lukeš J., Hashimi H. (2014) The dynamics of mitochondrial RNA-binding protein complex in Trypanosoma brucei and its petite mutant under optimized immobilization conditions Eukaryotic Cell 13 : 1232-1240.
DOI: 10.1128/EC.00149-14

Dokumenty ke stažení:
Huang_et_al_EC_2014 (pdf)
Ammerman M., Tomasello D., Faktorová D., Kafková L., Hashimi H., Lukeš J., Read L. (2013) A Core MRB1 Complex Component Is Indispensable for RNA Editing in Insect and Human Infective Stages of Trypanosoma brucei PLoS ONE 8 : e78015.
DOI: 10.1371/journal.pone.0078015

Dokumenty ke stažení:
Ammerman-PloSOne-2013 (pdf)
Cristodero M., Mani J., Oeljeklaus S., Aeberhard L., Hashimi H., Ramrath D., Lukeš J., Warscheid B., Schneider A. (2013) Mitochondrial translation factors of Trypanosoma brucei: Elongation factor-Tu has a unique subdomain that is essential for its function Molecular microbiology 90 : 744-755.
DOI: 10.1111/mmi.12397

Dokumenty ke stažení:
Cristodero-MM-2013 (pdf)
Hashimi H., Mcdonald L., Lukeš J., Stříbrná E. (2013) Trypanosome Letm1 Protein Is Essential for Mitochondrial Potassium Homeostasis Journal of Biological Chemistry 288 : 26914-26925.


Dokumenty ke stažení:
2013_Hashimi_JBC_26914 (pdf)
Hashimi H., Zimmer S., Ammerman M., Read L., Lukeš J. (2013) Dual core processing: MRB1 is an emerging kinetoplast RNA editing complex Trends in Parasitology 29 : 91-99.
DOI: 10.1016/j.pt.2012.11.005

Dokumenty ke stažení:
2013_Hashimi_Trends in Parasitol_91 (pdf)
Ammerman M., Downey K., Hashimi H., Fisk J., Tomasello D., Faktorova D., Kafkova L., King T., Lukeš J., Read L. (2012) Architecture of the trypanosome RNA editing accessory complex MRB1. Nucleic Acids Research 40 : 5637-5650.
DOI: 10.1093/nar/gks211

Dokumenty ke stažení:
2012_Ammerman_NAR_5637 (pdf)
Kafková L., Ammerman M., Faktorová D., Fisk J., Zimmer S., Sobotka R., Read L., Lukeš J., Hashimi H. (2012) Functional characterization of two paralogs that are novel RNA binding proteins influencing mitochondrial transcripts of Trypanosoma brucei RNA 18 : 1-16.


Dokumenty ke stažení:
2012_Kafkova_RNA_1 (pdf)
Ammerman M., Hashimi H., Novotná L., Číčová Z., Mcevoy S., Lukeš J., Read L. (2011) MRB3010 is a core component of the MRB1 complex that facilitates an early step of the kinetoplastid RNA editing process. RNA 17 : 865–877.
DOI: 10.1261/rna.2446311

Dokumenty ke stažení:
Ammerman et al. 2011 RNA (pdf)
Paris Z., Hashimi H., Lun S., Alfonzo J., Lukeš J. (2011) Futile import of tRNAs and proteins into the mitochondrion of Trypanosoma brucei evansi. Molecular and Biochemical Parasitology 176 : 116–120.
DOI: 10.1016/j.molbiopara.2010.12.010

Dokumenty ke stažení:
Paris et al. 2011 MBP (pdf)
Hashimi H., Benkovičová V., Čermáková P., Lai D., Horváth A., Lukeš J. (2010) The assembly of F1FO-ATP synthase is disrupted upon interference of RNA editing in Trypanosoma brucei. International Journal for Parasitology 40 : 45–54.
DOI: 10.1016/j.ijpara.2009.07.005

Dokumenty ke stažení:
Hashimi et al. 2010 IJP (pdf)
Lukeš J., Hashimi H., Verner Z., Číčová Z. (2010) The remarkable mitochondrion of trypanosomes and related flagellates. In: W. de Souza (Ed.), Structures and Organelles in Pathogenic Protists. Microbiology Monographs 17. Springer-Verlag, Berlin 228–252.
Hashimi H., Číčová Z., Novotná L., Wen Y., Lukeš J. (2009) Kinetoplastid guide RNA biogenesis is dependent on subunits of the mitochondrial RNA binding complex 1 and mitochondrial RNA polymerase. RNA 15 : 588-599.
DOI: 10.1261/rna.1411809

Dokumenty ke stažení:
Hashimi et al. 2009 RNA (pdf)
Hashimi H., Zíková A., Panigrahi A., Stuart K., Lukeš J. (2008) TbRGG1, an essential protein involved in kinetoplastid RNA metabolism that is associated with a novel multiprotein complex. RNA 14 : 970-980.
DOI: 10.1261/rna.888808

Dokumenty ke stažení:
Hashimi et al. 2008 RNA (pdf)

Více publikací

KONTAKT

Biologické centrum AV ČR, v.v.i.
Parazitologický ústav
Branišovská 1160/31
370 05 České Budějovice

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