Laboratoř molekulární ekologie a evoluce

Our research is mainly focused on molecular analysis of the co-evolution between hosts and parasitic or symbiotic organisms, including their biogeography, intraspecific variability and evolution of adaptations. We are also focused on investigation of the origin, evolution and phylogenetic relationships of parasitic organisms.

Řešené výzkumné projekty

Coevolution between Galápagos mockingbirds and their ectoparasites

Galapagos mockingbirds comprise four species of recently radiated passerines endemic to the Galapagos archipelago. Co-analysing mitochondrial and nuclear markers of mockingbirds and their ectoparasites the most likely scenario of colonisation of particular islands within the archipelago was reconstructed. Link between population size, geographical range and parasite load is being analysed using high-throughput sequencing of MHC genes and neutral multilocus markers. Obtaining knowledge of MHC gene diversity is also of conservation interest, since several species of mockingbirds are threatened or even extinct in their original area of distribution (e.g. Floreana mockingbird). 

Population genetics, demography and molecular evolution in rodents and their parasites

Adaptive and co-speciation components of host-parasite coevolution are studied in rodents and their parasites. Two rodent groups (voles and wood-mice) and their ectoparasites (lice, mites) as well as endoparasites (Eimeria) were selected as the model groups. Population structure was analysed using mitochondrial genes and selected nuclear markers. Despite observing lineages with relatively strict degree of host specificity, only limited amount of co-speciation was seen in both parasitic groups. Hence, the adaptive component of evolution seems to be the major driver defining genetic differentiation. Obtained patterns will be validated and explored in further detail using sequences of genes putatively under selection in the hosts (MHC II) and using multilocus and genomic data obtained from both counterparts.

 

Evolution of symbiotic bacteria associated with arthropods

We are broadly interested in intracellular symbiotic bacteria and their arthropod hosts. The main goal of our research is complex characterization of symbiotic systems in several model insect groups using microscopy, genomic, transcriptomic, and phylogenomic methods. Our main questions involve genome evolution of both the host and its symbionts, their phylogeny and populational structure, and host-symbiont-pathogen interactions. 
 

KONTAKT

Biologické centrum AV ČR, v.v.i.
Parazitologický ústav
Branišovská 1160/31
370 05 České Budějovice

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