Publications

Total found: 52 records
Chávez A.S.O., O´Neal A., Santambrogio L., Kotsyfakis M., Pedra J. (2019) Message in a Vesicle: Transkingdom Intercommunication at the Vector-Host Interface Journal of Cell Science 132: jcs224212.
DOI: 10.1242/jcs.224212
Chmelař J., Kotál J., Kovaříková A., Kotsyfakis M. (2019) The Use of Tick Salivary Proteins as Novel Therapeutics Frontiers in Physiology 10: 812.
DOI: 10.3389/fphys.2019.00812
Kotál J., Stergiou N., Buša M., Chlastáková A., Beránková Z., Řezáčová P., Langhansová H., Schwarz A., Calvo E., Kopecký J., Mareš M., Schmitt E., Chmelař J., Kotsyfakis M. (2019) The structure and function of Iristatin, a novel immunosuppressive tick salivary cystatin Cellular and Molecular Life Sciences 76: 2003–2013.
DOI: 10.1007/s00018-019-03034-3
Assumpção T., Mizurini D., Ma D., Monteiro R., Ahlstedt S., Reyes M., Kotsyfakis M., Mather T.N., Andersen J., Lukszo J., Ribeiro J., Francischetti I. (2018) Ixonnexin from tick saliva promotes fibrinolysis by interacting with plasminogen and tissue-type plasminogen activator, and prevents arterial thrombosis Scientific Reports 8: 4806.
DOI: 10.1038/s41598-018-22780-1
Hackenberg M., Kotsyfakis M. (2018) Exosome-Mediated Pathogen Transmission by Arthropod Vectors Trends in Parasitology 34: 549–552.
DOI: 10.1016/j.pt.2018.04.001
Chmelař J., Kotál J., Langhansová H., Kotsyfakis M. (2017) Protease inhibitors in tick saliva: the role of serpins and cystatins in tick-host-pathogen interaction Frontiers in Cellular and Infection Microbiology 7: 216.
DOI: 10.3389/fcimb.2017.00216
Hackenberg M., Langenberger D., Schwarz A., Erhart J., Kotsyfakis M. (2017) In silico target network analysis of de novo-discovered, tick saliva-specific microRNAs reveals important combinatorial effects in their interference with vertebrate host physiology RNA 23: 1259-1269.
DOI: 10.1261/rna.061168
Shaw D., McClure E.E., Kotsyfakis M., Pedra J. (2017) Tick saliva and microbial effector molecules: two sides of the same coin Arthropod Vector: Controller of Disease Transmission (Volume 2): Vector Saliva-Host-Pathogen Interactions, S.K. Wikel, S. Aksoy and G. Dimopoulos (Eds.) 169-194.
DOI: 10.1016/B978-0-12-805360-7.00010-1
Assumpção T., Ma D., Mizurini D., Kini R., Ribeiro J., Kotsyfakis M., Monteiro R., Francischetti I. (2016) In Vitro Mode of Action and Anti-thrombotic Activity of Boophilin, a Multifunctional Kunitz Protease Inhibitor from the Midgut of a Tick Vector of Babesiosis, Rhipicephalus microplus PLoS Neglected Tropical Diseases 10: e0004298.
DOI: 10.1371/journal.pntd.0004298
Chmelař J., Kotál J., Karim S., Kopáček P., Francischetti I., Pedra J., Kotsyfakis M. (2016) Sialomes and Mialomes: A Systems-Biology View of Tick Tissues and Tick-Host Interactions Trends in Parasitology 32: 242-254.
DOI: 10.1016/j.pt.2015.10.002
Chmelař J., Kotál J., Kopecký J., Pedra J., Kotsyfakis M. (2016) All for one and one for all on the tick–host battlefield Trends in Parasitology 32: 368-377.
DOI: 10.1016/j.pt.2016.01.004
Ferreira V., Vale V., Pangburn M., Abdeladhim M., Mendes-Sousa A., Coutinho-Abreu I., Rasouli M., Brandt E., Meneses C., Lima III K., Araújo R., Pereira M., Kotsyfakis M., Oliveira F., Kamhawi S., Ribeiro J., Gontijo N., Collin N., Valenzuela J.G. (2016) SALO, a novel classical pathway complement inhibitor from saliva of the sand fly Lutzomyia longipalpis Scientific Reports 6: 19300.
DOI: 10.1038/srep19300
Shaw D., Kotsyfakis M., Pedra J. (2016) For Whom the Bell Tolls (and Nods): Spit-acular Saliva Current Tropical Medicine Reports 3: 40-50.
DOI: 10.1007/s40475-016-0072-4
Tonk M., Bouchut A., Pierrot C., Pierce R., Kotsyfakis M., Rahnamaeian M., Vilcinskas A., Khalife J., Valdés J. J. (2016) Antiplasmodial activity is an ancient and conserved feature of tick defensins Frontiers in Microbiology 7: 1682.
DOI: 10.3389/fmicb.2016.01682
Wang X., Shaw D., Hammond H., Sutterwala F., Rayamajhi M., Shirey K., Perkins D., Bonventre J., Velayutham T., Evans S., Rodino K., VieBrock L., Scanlon K., Carbonetti N., Carlyon J., Miao E., McBride J., Kotsyfakis M., Pedra J. (2016) The prostaglandin E2-EP3 receptor axis regulates Anaplasma phagocytophilum-mediated NLRC4 inflammasome activation PLoS Pathogens 12: e1005803.
DOI: 10.1371/journal.ppat.1005803
Wang X., Shaw D., Sakhon O., Snyder G., Sundberg E., Santambrogio L., Sutterwala F., Dumler J., Shirey K., Perkins D., Richard K., Chagas A., Calvo E., Kopecký J., Kotsyfakis M., Pedra J. (2016) The tick protein sialostatin L2 binds to annexin A2 and inhibits NLRC4-mediated inflammasome activation Infection and Immunity 84: 1796-1805.
DOI: 10.1128/IAI.01526-15
Jablonka W., Kotsyfakis M., Mizurini D., Monteiro R., Lukszo J., Drake S., Ribeiro J., Andersen J. (2015) Identification and Mechanistic Analysis of a Novel Tick-Derived Inhibitor of Thrombin PLoS One 10: e0133991.
DOI: 10.1371/journal.pone.0133991
Klein M., Brühl T., Staudt V., Reuter S., Grebe N., Gerlitzki B., Hoffmann M., Bohn T., Ulges A., Stergiou N., De Graaf J., Löwer M., Taube C., Becker M., Hain T., Dietzen S., Stassen M., Huber M., Lohoff M., Campos Chagas A., Andersen J., Kotál J., Langhansová H., Kopecký J., Schild H., Kotsyfakis M., Schmitt E., Bopp T. (2015) Tick Salivary Sialostatin L Represses the Initiation of Immune Responses by Targeting IRF4-Dependent Transcription in Murine Mast Cells The Journal of Immunology 195: 621-631.
DOI: 10.4049/jimmunol.1401823
Kotál J., Langhansová H., Lieskovská J., Andersen J., Francischetti I., Chavakis T., Kopecký J., Pedra J., Kotsyfakis M., Chmelař J. (2015) Modulation of host immunity by tick saliva Journal of Proteomics 128: 58-68.
DOI: 10.1016/j.jprot.2015.07.005
Kotsyfakis M., Kopáček P., Franta Z., Pedra J., Ribeiro J. (2015) Deep Sequencing Analysis of the Ixodes ricinus Haemocytome PLOS Neglected Tropical Diseases 9: e0003754.
DOI: 10.1371/journal.pntd.0003754

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