Mgr. Jan Perner, Ph.D.

Job Position: Research Scientist - Laboratory of Vector Immunology

Contact details

Phone: +420 38777 5489
E-mail: perner@paru.cas.cz
Room: 337

Curriculum vitae

• 2019 – now Principal Investigator 
  Institute of Parasitology, Biology Centre, Czech Republic
• 2017 – now Post - doc 
  Institute of Parasitology, Biology Centre, Czech Republic

• Testing of new acaricide for elimination of red poultry mite infestation in farming - Technology Agency of the Czech Republic. Principal Investigator
• Nutritional factors essential for tick development and reproduction - Czech Science Foundation. Post-doc Team Member
• Midgut microbial ecology, epithelial immunity, and vector competence of Ixodes ricinus and Amblyomma americanum Czech Science Foundation. Post-doc Team Member
• Centre for research of pathogenicity and virulence of parasites. European Regional Development Fund and Ministry of Education, Youth and Sport. Post-doc Team Member

• Perner J, Kropáčková S, Kopáček P, Ribeiro JMC (2018) Sialome diversity of ticks revealed by RNAseq of single tick salivary glands; PLoS Neglected Tropical Diseases 12:e0006410.
• Perner J, Kotál J, Hatalová T, Urbanová V, Bartošová-Sojková P, Brophy PM, Kopáček P (2018) Inducible glutathione S-transferase (IrGST1) from the tick Ixodes ricinus is a haem-binding protein; Insect Biochemistry and Molecular Biology 95, 44–54.
• Hartmann D, Šíma R, Konvičková J, Perner J, Kopáček P, Sojka D (2018) Multiple legumain isoenzymes in ticks; International Journal for Parasitology 48, 167–178.
• Palus M, Vancová M, Širmarová J, Elsterová J, Perner J, Růžek D (2017) Tick-borne encephalitis virus infects human brain microvascular endothelial cells without compromising blood-brain barrier integrity; Virology 507, 110–122.
• Perner J, Sobotka R, Šíma R, Konvičková J, Sojka D, Oliveira PL, Hajdušek O, Kopáček P (2016) Acquisition of exogenous haem is essential for tick reproduction; eLife 5:e12318.
• Perner J, Provazník J, Schrenková J, Urbanová V, Ribeiro JMC, Kopáček P (2016) RNA-seq analyses of the midgut from blood- and serum-fed Ixodes ricinus ticks; Scientific Reports 6, 36695.
• Hajdušek O, Šíma R, Perner J, Loosová G, Harcubová A, Kopáček P (2016) Tick iron and heme metabolism - New target for an anti-tick intervention; Ticks and Tick Borne Diseases 7, 565–572.
• Sojka D, Pytelková J, Perner J, Horn M, Konvičková J, Schrenková J, Mareš M, Kopáček P (2016) Multienzyme degradation of host serum albumin in ticks; Ticks and Tick Borne Diseases 7, 604–613.
• Storm J, Perner J, Aparicio I, Patzewitz EM, Olszewski K, Llinas M, Engel PC, Müller S (2011) Plasmodium falciparum glutamate dehydrogenase a is dispensable and not a drug target during erythrocytic development; Malaria Journal 10:193.

• Perner J, Gasser RB, Oliveira PL, Kopáček P (2019) Haem Biology in Metazoan Parasites - 'The Bright Side of Haem'; Trends in Parasitology 35, 213–225
• Hajdušek O, Síma R, Ayllón N, Jalovecká M, Perner J, de la Fuente J, Kopáček P (2013) Interaction of the tick immune system with transmitted pathogens; Frontiers in Cellular and Infection Microbiology 3:26;
• Commentary:
• Kopáček P, Perner J (2016) Vector Biology: Tyrosine Degradation Protects Blood Feeders from Death via La Grande Bouffe; Current Biology 26, R763–R765.

• Kopáček P, Perner J, Sojka D, Šíma R, Hajdušek O (2018) Molecular Targets to Impair Blood Meal Processing in Ticks. Meng ChQ, Sluder AE, and Selzer PM (Eds). Ectoparasites: Drug Discovery Against Moving Targets; Wiley 139–165.

• Utility model (2017-34038): A membrane-based device for breeding and testing adult ticks
• Utility model (2018-35307): A feeder for breeding and testing ticks in the larval and nymphal stage

Publications