Publications

Total found: 80 records
Eyer L., Fojtikova M., Nencka R., Rudolf I., Hubálek Z., Růžek D. (2019) Viral RNA-Dependent RNA Polymerase Inhibitor 7-Deaza-2'-C-Methyladenosine Prevents Death in a Mouse Model of West Nile Virus Infection Antimicrobial Agents and Chemotherapy 63: e02093-18.
DOI: 10.1128/AAC.02093-18
Hönig V., Švec P., Marek L., Mrkvička T., Zubrikova D., Wittmann M., Masař O., Szturcová D., Růžek D., Pfister K., Grubhoffer L. (2019) Model of Risk of Exposure to Lyme Borreliosis and Tick-Borne Encephalitis Virus-Infected Ticks in the Border Area of the Czech Republic (South Bohemia) and Germany (Lower Bavaria and Upper Palatinate) International Journal of Environmental Research and Public Health 16: 1173.
DOI: 10.3390/ijerph16071173
Krol E., Wandzik I., Brzuska G., Eyer L., Růžek D., Szewczyk B. (2019) Antiviral Activity of Uridine Derivatives of 2-Deoxy Sugars against Tick-Borne Encephalitis Virus Molecules 24: 1129.
DOI: 10.3390/molecules24061129
Růžek D., Avšič Županc T., Borde J., Chrdle A., Eyer L., Karganova G. , Kholodilov I., Knap N., Kozlovskya L., Matveev A., Miller A., Osoldkin D.I., Överby A.K., Titukonova N. , Tkachev S., Zajkowska J. (2019) Tick-borne encephalitis in Europe and Russia: Review of pathogenesis, clinical features, therapy, and vaccines Antiviral Research 164: 23–51.
DOI: 10.1016/j.antiviral.2019.01.014
Eyer L., Nencka R., De Clercq E., Seley-Radtke K., Růžek D. (2018) Nucleoside analogs as a rich source of antiviral agents active against arthropod-borne flaviviruses. vAntiviral Chemistry and Chemotherapy 26: 1-28.
DOI: 10.1177/2040206618761299
Füzik T., Formanová P., Růžek D., Yoshii K., Niedrig M., Plevka P. (2018) Structure of tick-borne encephalitis virus and its neutralization by a monoclonal antibody Nature Communications 9: 436.
DOI: 10.1038/s41467-018-02882-0
Haviernik J., Štefánik M., Fojtikova M., Kali S., Noël T., Rudolf I., Hubálek Z., Růžek D., Eyer L. (2018) Arbidol (Umifenovir): A Broad-Spectrum Antiviral Drug That Inhibits Medically Important Arthropod-Borne Flaviviruses. Viruses 10: 184.
DOI: 10.3390/v10040184
Müllerová J., Elsterová J., Černý J., Ditrich O., Žárský J., Culler L.E., Kampen H., Walther D., Coulson S., Růžek D., Grubhoffer L. (2018) No indication of arthropod-vectored viruses in mosquitoes (Diptera: Culicidae) collected on Greenland and Svalbard Polar Biology 11: 1581–1586.
DOI: 10.1007/s00300-017-2242-9
Palus M., Sohrabi Y., Broman K.W., Strnad H., Šíma M., Růžek D., Volkova V., Slapničková M., Vojtíšková J. , Mrázková L., Salát J., Lipoldová M. (2018) A novel locus on mouse chromosome 7 that influences survival after infection with tick-borne encephalitis virus. BMC Neuroscience 19: 39.
DOI: 10.1186/s12868-018-0438-8
Růžek D., Yoshii K., Bloom M.E., Gould E. (2018) Tick-borne encephalitis virus - Virology. In: G. Dobler, W. Erber and H.-J. Schmitt (Eds.), Tick-Borne Encephalitis (TBE) Springer 12–26.
Salát J., Formanová P., Huňady M., Eyer L., Palus M., Růžek D. (2018) Development and testing of a new tick-borne encephalitis virus vaccine candidate for veterinary use Vaccine 36: 7257–7261.
DOI: 10.1016/j.vaccine.2018.10.034
Šebera J., Dubánková A., Sychrovský V., Růžek D., Boura E., Nencka R. (2018) The structural model of Zika virus RNA-dependent RNA polymerase in complex with RNA for rational design of novel nucleotide inhibitors Scientific Reports 8: 11132.
DOI: 10.1038/s41598-018-29459-7
Širmarová J., Salát J., Palus M., Hönig V., Langhansová H., Holbrook M., Růžek D. (2018) Kyasanur Forest disease virus infection activates human vascular endothelial cells and monocyte-derived dendritic cells Emerging Microbes & Infections 7: 175.
DOI: 10.1038/s41426-018-0177-z
Štefánik M., Formanová P., Bílý T., Vancová M., Eyer L., Palus M., Salát J., Braconi C. T. , Zanotto De A. P., Gould E., Růžek D. (2018) Characterisation of Zika virus infection in primary human astrocytes. BMC Neuroscience BMC Neuroscience 18: 1136.
DOI: 10.1186/s12868-018-0407-2
Bukin Y.S., Dzhioev Y.S., Tkachev S., Kozlova I., Paramonov A.I., Růžek D., Qu Z., Zlobin V.I. (2017) A comparative analysis on the physicochemical properties of tick-borne encephalitis virus envelope protein residues that affect its antigenic properties Virus Research 238: 124-132.
DOI: 10.1016/j.virusres.2017.06.006
Demina T.V., Tkachev S., Kozlova L., Doroshenko K., Lisak O.V., Suntsova O.V., Verkhozina M.M., Dzhioev Y., Paramonov A.I., Tikunov A.Y., Tikunova N.V., Zlobin V.I., Růžek D. (2017) Comparative analysis of complete genome sequences of European subtype tick-borne encephalitis virus strains isolated from Ixodes persulcatus ticks, long-tailed ground squirrel (Spermophilus undulatus), and human blood in the Asian part of Russia Ticks and Tick-borne Diseases 8: 547-553.
DOI: 10.1016/j.ttbdis.2017.03.002
Elsterová J., Palus M., Širmarová J., Kopecký J., Niller H., Růžek D. (2017) Tick-borne encephalitis virus neutralization by high dose intravenous immunoglobulin Ticks and Tick-borne Diseases 8: 253-258.
DOI: 10.1016/j.ttbdis.2016.11.007
Eyer L., Kondo H., Zouharova D., Hirano M., Valdés J. J., Muto M., Kasti T., Kobayashi S., Haviernik J., Igarashi M., Kariwa H., Vaculovicova M., Černý J., Kizek R., Kröger A., Lienenklaus S., Dejmek M., Nencka R., Palus M., Salát J., De Clercq E., Yoshii K., Růžek D. (2017) Escape of Tick-Borne Flavivirus from 2′-C-Methylated Nucleoside Antivirals Is Mediated by a Single Conservative Mutation in NS5 That Has a Dramatic Effect on Viral Fitness Journal of Virology 91: e01028-17.
DOI: 10.1128/JVI.01028-17
Eyer L., Zouharova D., Širmarová J., Fojtikova M., Štefánik M., Haviernik J., Nencka R., De Clercq E., Růžek D. (2017) Antiviral activity of the adenosine analogue BCX4430 against West Nile virus and tick-borne flaviviruses Antiviral Research 142: 63-67.
DOI: 10.1016/j.antiviral.2017.03.012
Hercík K., Kozák J., Šála M., Dejmek M., Hřebabecký H., Zborníková E., Smola M., Růžek D., Nencka R., Boura E. (2017) Adenosine triphosphate analogs can efficiently inhibit the Zika virus RNA-dependent RNA polymerase. Antiviral Research 137: 131-133.
DOI: 10.1016/j.antiviral.2016.11.020

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Biology Centre CAS
Institute of Parasitology
Branišovská 1160/31
370 05 České Budějovice

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