RNDr. Jiří Týč, Ph.D.

Job Position: Research Scientist - Laboratory of Electron Microscopy

Contact details

Phone: +420 387 77 5485
E-mail: jiri.tyc@paru.cas.cz
Room: 407


My main research interest is BIOIMAGING. I got my Ph.D. in molecular biology and I started with 3D EM during my postdoc at Bioimaging unit in Oxford (UK) at Oxford Brookes University.  I focus on electron microscopy, but I have experience also with confocal and high-resolution fluorescence microscopy. I specialize in 3D SEM techniques such as SBF-SEM (serial block-face scanning electron microscopy) and array tomography. 


Scopus Author ID: 35785427300

Total found: 12 records
Konopová B., Týč J. (2023) Minimal resin embedding of SBF-SEM samples reduces charging and facilitates finding a surface-linked region of interest. Frontiers in Zoology 20 : article number: 29.
DOI: 10.1186/s12983-023-00507-x
Pilátová J., Tashyreva D., Týč J., Vancová M., Bokhari S. N. H., Skoupý R., Klementová M., Küpper H., Mojzeš P., Lukeš J. (2023) Massive accumulation of strontium and barium in diplonemid protists mBio 14 : 1.
DOI: 10.1128/mbio.03279-22

Documents to download:
Pilatova_2023_mBio (pdf)
Sheikh S., Pánek T., Gahura O., Týč J., Záhonová K., Lukeš J., Eliáš M., Hashimi H. (2023) A novel group of dynamin-related proteins shared by eukaryotes and giant viruses is able to remodel mitochondria from within the matrix Molecular Biology and Evolution 40 : msad134.
DOI: 10.1093/molbev/msad134

Documents to download:
Sheikh_2023_MolBiolEvol (pdf)
Zakharova A., Saura A., Morales J., Tashyreva D., Butenko A., Svobodová M., Poschmann G., Nandipati S., Zakharovová A., Noyvert D., Gahura O., Týč J., Stühler K., Kostygov A., Nowack E.C.M., Lukeš J., Yurchenko V. (2023) A neo-functionalized homolog of host transmembrane protein controls localization of bacterial endosymbionts in the trypanosomatid Novymonas esmeraldas Current Biology 33 : 2690-2701.
DOI: 10.1016/j.cub.2023.04.060

Documents to download:
Zakharova_2023_CB (pdf)
Týč J., Novotná L., Pena Diaz C., Maslov D., Lukeš J. (2017) RSM22, mtYsxC and PNKD-like proteins are required for mitochondrial translation in Trypanosoma brucei Mitochondrion 34 : 67-74.
DOI: 10.1016/j.mito.2017.01.003

Documents to download:
Tyc et al. 2017 Mitochondrion (pdf)
Zíková A., Hampl V., Paris Z., Týč J., Lukeš J. (2016) Aerobic mitochondria of parasitic protists: diverse genomes and complex functions. Molecular and Biochemical Parasitology 209 : 46-57.
DOI: 10.1016/j.molbiopara.2016.02.007

Documents to download:
Zikova et al. 2016 MBP (pdf)
Týč J., Klingbeil M., Lukeš J. (2015) Mitochondrial Heat Shock Protein Machinery Hsp70/Hsp40 Is Indispensable for Proper Mitochondrial DNA Maintenance and Replication mBio 6 : e02425-14.
DOI: 10.1128/mBio.02425-14

Documents to download:
Tyc_et_al_mBio_2015 (pdf)
Verner Z., Basu S., Benz C., Dixit S., Dobáková E., Faktorová D., Hashimi H., Horáková E., Huang Z., Paris Z., Pena P., Ridlon L., Týč J., Wildridge D., Zíková A., Lukeš J. (2015) The malleable mitochondrion of Trypanosoma brucei Internation Review of Cell and Molecular Biology 315 : 73-151.
DOI: 10.1016/bs.ircmb.2014.11.001

Documents to download:
Verner-IRCMB-2015 (pdf)
Lukeš J., Skalický T., Týč J., Votýpka J., Yurchenko V. (2014) Evolution of parasitism in kinetoplastid flagellates Molecular & biochemical parasitology 195 : 115-122.
DOI: 10.1016/j.molbiopara.2014.05.007

Documents to download:
Lukes-MBP-2014 (pdf)
Týč J., Votýpka J., Klepetková H., Šuláková H., Jirků M., Lukeš J. (2013) Growing diversity of trypanosomatid parasites of flies (Diptera: Brachycera): frequent cosmopolitism and moderate host specificity. Molecular Phylogenetics and Evolution 69 : 255-264.
DOI: 10.1016/j.ympev.2013.05.024

Documents to download:
2013_Týč_MPE_255 (pdf)
Týč J., Faktorová D., Kriegová E., Jirků M., Vávrová Z., Maslov D., Lukeš J. (2010) Probing for primary functions of prohibitin in Trypanosoma brucei. International Journal for Parasitology 40 : 73–83.
DOI: 10.1016/j.ijpara.2009.07.008

Documents to download:
Tyc et al. 2010 IJP (pdf)
Týč J., Long S., Jirků M., Lukeš J. (2010) YCF45 protein, usually associated with plastids, is targeted into the mitochondrion of Trypanosoma brucei. Molecular and Biochemical Parasitology 173 : 43–47.
DOI: 10.1016/j.molbiopara.2010.05.002

Documents to download:
Tyc et al. 2010 MBP (pdf)


Biology Centre CAS
Institute of Parasitology
Branišovská 1160/31
370 05 České Budějovice

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