RNDr. Drahomíra Faktorová, Ph.D.

Job Position: Research Scientist - Laboratory of Molecular Biology of Protists

Contact details

Phone: +420 387775443
E-mail: dranov@paru.cas.cz
Room: PARU II, 1. patro

Curriculum vitae

Publlications before 2007:

Vališ K., Mašek T., Novotná D., Pospíšek M., Janderová B. (2006) Immunity to killer toxin K1 is connected with the Golgi-to-vacuole protein degradation pathway. Folia Microbiologica 51: 196-202.
Novotná D., Flegelová H., Janderová B. (2004) Different action of killer toxins K1 and K2 on the plasma membrane and the cell wall of Saccharomyces cerevisiae. FEMS Yeast Res. 4: 803-813.
Flegelová H., Chaloupka R., Novotná D., Maláč J., Gášková D., Sigler K., Janderová B. (2003) Changes in plasma membrane fluidity lower the sensitivity of S. cerevisiae to killer toxin K1. Folia Microbiologic48: 761-766.
Flegelová H., Novotná D., Vojtíšková K., Janderová B. (2002): Isolation and characterization of Saccharomyces cerevisiae mutants with a different degree of resistance to killer toxins K1 and K2. FEMS Yeast Res2: 73-79.

Total found: 20 records
Faktorová D., Kaur B., Valach M., Graf L., Benz C., Burger G., Lukeš J. (2020) Targeted integration by homologous recombination enables in situ tagging and replacement of genes in the marine microeukaryote Diplonema papillatum Environmental Microbiology 22 : 3660–3670.
DOI: 10.1111/1462-2920.15130

Documents to download:
Faktorová_2020_Env_Microbiology (pdf)
Faktorová D., Nisbet E.R., Kachale A., Kaur B., et al., Lukeš J. (2020) Genetic tool development in marine protists: emerging model organisms for experimental cell biology Nature Methods 17 : 481–494.
DOI: 10.1038/s41592-020-0796-x

Documents to download:
Faktorova_2020_NatureMethods (pdf)
Horáková E., Faktorová D., Kraeva N., Kaur B., Van Den Abbeele J., Yurchenko V., Lukeš J. (2020) Catalase compromises the development of the insect and mammalian stages of Trypanosoma brucei FEBS Journal 287 : 964–977.
DOI: 10.1111/febs.15083

Documents to download:
Horakova_2020_FEBSJournal (pdf)
Kaur B., Záhonová K., Valach M., Faktorová D., Prokopchuk G., Burger G., Lukeš J. (2020) Gene fragmentation and RNA editing without borders: eccentric mitochondrial genomes of diplonemids Nucleic Acids Research 48 : 2694–2708.
DOI: 10.1093/nar/gkz1215

Documents to download:
Kaur_2020_Nucleic Acids Research (pdf)
Faktorová D., Bär A., Hashimi H., McKenney K., Horák A., Schnaufer A., Rubio M., Alfonzo J., Lukeš J. (2018) TbUTP10, a protein involved in early stages of pre-18S rRNA processing in Trypanosoma brucei Molecular and Biochemical Parasitology 225 : 84–93.
DOI: 10.1016/j.molbiopara.2018.09.003

Documents to download:
Faktorova_et al._2018 (pdf)
Faktorová D., Valach M., Kaur B., Burger G., Lukeš J. (2018) Mitochondrial RNA editing and processing in diplonemid protists. In: M.W. Gray and J. Cruz-Reyes (Eds.), RNA Metabolism in Mitochondria Springer 145–176.
DOI: 10.1007/978-3-319-78190-7_6

Documents to download:
Faktorova et.al 2018_chapter_RNA Metabolism in Mitochondria (pdf)
Kaur B., Valach M., Pena Diaz C., Moreira S., Keeling P., Burger G., Lukeš J., Faktorová D. (2018) Transformation of Diplonema papillatum, the type species of the highly diverse and abundant marine micro-eukaryotes Diplonemida (Euglenozoa Environmental Microbiology 20 : 1030-1040.
DOI: 10.1111/1462-2920.14041

Documents to download:
Kaur_et_al._Environmental Microbiology_2018 (pdf)
Tashyreva D., Prokopchuk G., Yabuki A., Kaur B., Faktorová D., Votýpka J., Kusaka Ch., Fujikura K. , Shiratori T., Ishida K., Horák A., Lukeš J. (2018) Phylogeny and morphology of new diplonemids from Japan Protist 169 : 158–179.
DOI: 10.1016/j.protis.2018.02.001

Documents to download:
Tashyreva_et.al_Protist_2018 (pdf)
Faktorová D., Dobáková E., Pena Diaz C., Lukeš J. (2016) From simple to supercomplex: mitochondrial genomes of euglenozoan protists f1000Research 5 : 392.
DOI: 10.12688/f1000research.8040.1

Documents to download:
Faktorova et al. 2016 F1000research (pdf)
Ishemgulova A., Kraeva N., Faktorová D., Podešvová L., Lukeš J., Yurchenko V. (2016) T7 polymerase-driven transcription is downregulated in metacyclic promastigotes and amastigotes of Leishmania mexicana Folia Parasitologica 63 : 016.
DOI: 10.14411/fp.2016.016

Documents to download:
Ishemgulova et al. 2016 FP (pdf)
Valach M., Moreira S., Faktorová D., Lukeš J., Burger G. (2016) Post-transcriptional remodeling of genes: a look under the hood of mitochondrial gene expression in diplonemids RNA Biology 13 : 1204-1211.
DOI: 10.1080/15476286.2016.1240143

Documents to download:
Valach et al. 2016 RNA Biol (pdf)
Huang Z., Faktorová D., Křížová A., Kafková L., Read L., Lukeš J., Hashimi H. (2015) Integrity of the core mitochondrial RNA-binding complex 1 is vital for trypanosome RNA editing RNA 21 : 2088-2102.
DOI: 10.1261/rna.052340.115

Documents to download:
Huang et al 2015 RNA (pdf)
Verner Z., Basu S., Benz C., Dixit S., Dobáková E., Faktorová D., Hashimi H., Horáková E., Huang Z., Paris Z., Pena P., Ridlon L., Týč J., Wildridge D., Zíková A., Lukeš J. (2015) The malleable mitochondrion of Trypanosoma brucei Internation Review of Cell and Molecular Biology 315 : 73-151.
DOI: 10.1016/bs.ircmb.2014.11.001

Documents to download:
Verner-IRCMB-2015 (pdf)
Ammerman M., Tomasello D., Faktorová D., Kafková L., Hashimi H., Lukeš J., Read L. (2013) A Core MRB1 Complex Component Is Indispensable for RNA Editing in Insect and Human Infective Stages of Trypanosoma brucei PLoS ONE 8 : e78015.
DOI: 10.1371/journal.pone.0078015

Documents to download:
Ammerman-PloSOne-2013 (pdf)
Ammerman M., Downey K., Hashimi H., Fisk J., Tomasello D., Kafkova L., Faktorová D., King T., Lukeš J., Read L. (2012) Architecture of the trypanosome RNA editing accessory complex MRB1. Nucleic Acids Research 40 : 5637-5650.
DOI: 10.1093/nar/gks211

Documents to download:
2012_Ammerman_NAR_5637 (pdf)
Kafková L., Ammerman M., Faktorová D., Fisk J., Zimmer S., Sobotka R., Read L., Lukeš J., Hashimi H. (2012) Functional characterization of two paralogs that are novel RNA binding proteins influencing mitochondrial transcripts of Trypanosoma brucei RNA 18 : 1-16.

Documents to download:
2012_Kafkova_RNA_1 (pdf)
Týč J., Faktorová D., Kriegová E., Jirků M., Vávrová Z., Maslov D., Lukeš J. (2010) Probing for primary functions of prohibitin in Trypanosoma brucei. International Journal for Parasitology 40 : 73–83.
DOI: 10.1016/j.ijpara.2009.07.008

Documents to download:
Tyc et al. 2010 IJP (pdf)
Gile G., Faktorová D., Castlejohn C., Burger G., Lang B., Farmer M., Lukeš J., Keeling P. (2009) Distribution and phylogeny of EFL and EF-1? in Euglenozoa suggest ancestral co-occurrence followed by differential loss. PLoS ONE 4 : e5162.
DOI: 10.1371/journal.pone.0005162

Documents to download:
Gile et al. 2009 PLoS ONE (pdf)
Roy J., Faktorová D., Benada O., Lukeš J., Burger G. (2007) Description of Rhynchopus euleeides n. sp. (Diplonemea), a free-living, marine euglenozoan. Journal of Eukaryotic Microbiology 54 : 137-145.
DOI: 10.1111/j.1550-7408.2007.00244.x

Documents to download:
Roy et al. 2007 JEM (pdf)
Roy J., Faktorová D., Lukeš J., Burger G. (2007) Unusual mitochondrial genome structure throughout Euglenozoa. Protist 158 : 385-396.
DOI: 10.1016/j.protis.2007.03.002

Documents to download:
Roy et al. 2007 Protist (pdf)


Biology Centre CAS
Institute of Parasitology
Branišovská 1160/31
370 05 České Budějovice

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