RNDr. Martin Palus, Ph.D.
Job Position: Head of Laboratory - Laboratory of Arbovirology
Phone:
+420 387775145
E-mail:
palus@paru.cas.cz
Room:
313c/324
Research interests
My research activity is the study of human viral infections, disease development and its treatment options.
Interest is focused on tick-borne encephalitis virus and related viruses transmitted by ticks and mosquitoes, as well as other viruses that require attention, such as SARS-CoV2.
Education
Faculty of Science, University of South Bohemia in Ceske Budejovice, Czech Republic
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2012-2016 |
Ph.D. (hons.) |
Infectious Biology |
Tick-borne encephalitis – from pathogenesis to therapy |
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2015 |
RNDr. |
Clinical Biology |
Mice with different susceptibility to tick-borne encephalitis virus infection show selective neutralizing antibody response and inflammatory reaction in the central nervous system |
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2009-2012 |
MSc. |
Clinical Biology |
The role of the host genetic background on the pathogenesis of tick-borne encephalitis |
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2007-2009 2006-2009 |
BSc. (hons.) |
Biology Biology-Biomedical Laboratory Techniques |
Study of the pathogenesis of tick-borne encephalitis in hosts with different genetic and immunological background |
Employment
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2014-present: |
Researcher |
Emerging Viral Diseases, Veterinary Research Institute, Brno, Czech Republic |
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2011-present: |
Head of Lab |
Laboratory of Arbovirology Institute of Parasitology, Biology Centre, Czech Academy of the Sciences |
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2011-2012: |
Assistant |
Laboratory of Biological Monitoring and Protection, The National Institute for Nuclear, Chemical and Biological Protection, Czech Republic |
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2009: |
Assistant |
Dept. of Parasite Immunology , Institute of Parasitology, Biology Centre, Czech Academy of the Sciences |
Research Funding (PI)
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2023 |
Neuropathogenesis linked to NS1 protein of tick-borne encephalitis virus; The Czech Science Foundation (GACR); (2023 - 2025) |
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2022 |
Verification of the possibility of using a mouse antibody against the protein of the tick-borne encephalitis virus for the purposes of diagnosis of tick-borne encephalitis by the ELISA method; Technology Agency of the Czech Republic GAMA2; |
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2020: |
Neurovascular unit cells interactions leading to the blood-brain barrier breakdown during tick-borne encephalitis; The Czech Science Foundation (GACR); (2020 - 2022) |
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2020: |
Identification and characterization of TBEV-neutralizing and cross-reactive antibodies from individuals that are convalescent from flaviviral infection; Programme for research and mobility support of starting researchers from Czech Academy of Sciences (2020-2021) |
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2017: |
Programme of Support of Postdoctoral Fellowships from Czech Academy of Sciences (2017-2018) |
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2015: |
Role of the human brain microvascular endothelial cells during tick-borne encephalitis virus infection in the central nervous system; Grant Agency of the University of South Bohemia |
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2014: |
Role of the human non-neural cells in the neuronal injury during tick-borne encephalitis; Grant Agency of the University of South Bohemia in Ceske Budejovice |
Postgraduate Courses and Internships
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2020-2021: |
Internship: Immunology and Infectious Disease (Davide Robbiani), Institute for Research in Biomedicine, Switzerland |
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2014: |
PREDEMICS, National Institute for Infectious Diseases “L. Spallanzani” – Rome: Workshop on zoonotic features of viral infections from the animal reservoir to pandemic emergence |
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2012: |
Institute of Postgraduate Education in Medicine in Prague: Methods in Laboratory Medicine (accredited qualification course) |
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2011: |
Erasmus Programme: Arbovirus Pathogenesis Group, The Roslin Institute and Royal (Dick)School of Veterinary Studies, The University of Edinburgh (4 mos.) |
Honors
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2021: |
Prize by the President of Czech Academy of Sciences for young scientists for outstanding results |
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2018: |
Otto Wichterle's Award for selected, exceptionally high-quality and promising scientists from the Czech Academy of Sciences |
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2017: |
Dean’s Award for excellent scientific results during Ph.D. studies. Faculty of Science, University of South Bohemia |
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2015: |
Award for the best Czech and Slovak young microbiologist of the year (Czechoslovak Society for Microbiology; XXIV. Tomasek Days of young microbiologists, Brno) |
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2013: |
Best poster award (Moscow, “Chumakov IPVE” RAMS, Up-to-date problems of TBE) |
Publications
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ORCID ID: 0000-0002-4279-7092 |
WoS RID: N-1263-2017 |
Scopus Author ID=25825507600 |
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Selected conferences contribution (talk/poster)
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2023 |
15th International Symposium on Ticks and Tick-borne Diseases; Germany, Weimar (invited) |
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2022 |
10th Tick and Tick-Borne Pathogen Conference, Murighiol, Romania |
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2022 |
Konference: Národní institut virologie a bakteriologie, Czech Republic, Kutná Hora |
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2022 |
XXIV. Hradecké virologické dny, Czech Republic, Hradec Králové |
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2022 |
24th International Symposium on Signal Transduction at the Blood-Brain Barriers, Bari, Italy |
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2019: |
22nd International Symposium on Signal Transduction at The Blood-Brain Barriers, Germany, Würzburg |
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2019: |
The 67th Annual Meeting of the Japanese Society for Virology, Japan, Tokyo |
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2019: |
Joint CzechoSlovak Virology Conference 2019 and 1st SK-AT Structural Virology Meeting, Bratislava |
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2018: |
21nd International Symposium on Signal Transduction at the Blood Brain Barriers, Romania, Arad |
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2018: |
28. Pečenkovy epidemiologické dny, České Budějovice |
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2017: |
Tick and Tick-borne Pathogens 9 (One Health), Australia, Cairns |
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2017: |
Joint CzechoSlovak Virology Conference 2017, České Budějovice |
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2015: |
International Symposium on Flaviviruses: Structure and Immunity, Austria, Vienna |
Selected applied research
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0550809 - FZÚ 2022 RIV CZ cze L - Prototyp, funkční vzorek Antifoulingový povrch biočipu s terpolymerní vrstvou postmodifikovanou specifickou protilátkou pro kvantitativní stanovení viru SARS-CoV-2 v klinických vzorcích pomocí metody QCM. |
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0555327 - BC 2022 RIV cze P1 - Užitný vzor, průmyslový vzor Sada primerů pro amplifikační kontrolu pro detekci koronaviru SARS-CoV-2 metodou izotermické amplifikace LAMP a kit pro detekci koronaviru SARS-CoV-2 metodou izotermické amplifikace LAMP. |
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0542199 - FZÚ 2022 RIV CZ cze L - Prototyp, funkční vzorek Ultra-rezistentní povrch biočipu s terpolymerní vrstvou postmodifikovanou specifickou protilátkou pro rychlou detekci viru SARS-CoV-2 pomocí metody QCM. |
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0537039 - FZÚ 2021 RIV CZ cze L - Prototyp, funkční vzorek Funkční biočip s ultra-rezistentní polymerní vrstvou pro rychlou detekci viru SARS-CoV-2 pomocí metody QCM. |
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O - Ostatní výsledky, 2015, Detection of tick-borne encephalitis virus subtypes by RT-qPCR; Předkladatel: Státní ústav jaderné, chemické a biologické ochrany, v.v.i., Dodavatel: MV0 - Ministerstvo vnitra |
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O - Ostatní výsledky, 2015, Virus Serotyping by TaqMan and SYTO 9 in Single Reaction; Předkladatel: Státní ústav jaderné, chemické a biologické ochrany, v.v.i., Dodavatel: MV0 - Ministerstvo vnitra |
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O - Ostatní výsledky, 2014, Flavivirus Detection by Quantitative PCR; Předkladatel: Státní ústav jaderné, chemické a biologické ochrany, v.v.i., Dodavatel: MV0 - Ministerstvo vnitra |
Other
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Member of the International Brain Barriers Society (IBBS) |
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Member of the World Society for Virology (WSV) |
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Member of the Czechoslovak Society for Microbiology |
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Member of the Scientific Council of Institute of Parasitology, Biology Centre CAS |
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Certificate for the sex and gender dimension of biomedical research completed Libra course |
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Certificate for the performance of diagnostic methods and preparation of medications (Institute for Postgraduate education in Medicine, Prague) |
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Certificate of competency according to § 15d of the Act No. 246/1992 coll. on Protection Animals against Cruelty in present statues at large. Czech University of Life Sciences in Prague, Central commission for Animal Welfare (CCAW) |
