Publications

Total found: 41 records
Jalovecká M., Hartmann D., Miyamoto Y., Eckmann L. , Hajdušek O., O´Donoghue A.J. , Sojka D. (2018) Validation of Babesia proteasome as a drug target International Journal for Parasitology-Drugs and Drug Resistance 8: 394–402.
DOI: 10.1016/j.ijpddr.2018.08.001
Kopáček P., Perner J., Sojka D., Šíma R., Hajdušek O. (2018) Molecular Targets to Impair Blood Meal Processing in Ticks. In: Ch. Q. Meng, A. E. Sluder and P.M Selzer (Eds.), Ectoparasites: Drug Discovery Against Moving Targets Wiley 139–165.
DOI: 10.1002/9783527802883
Perner J., Sobotka R., Šíma R., Konvičková J., Sojka D., Lagerblad de Oliveira P., Hajdušek O., Kopáček P. (2016) Acquisition of exogenous haem is essential for tick reproduction eLife 5: e12318.
DOI: 10.7554/eLife.12318
Sojka D., Hartmann D., Bartošová-Sojková P., Dvořák J. (2016) Parasite Cathepsin D-Like Peptidases and Their Relevance as Therapeutic Targets Trends in Parasitology 32: 708-723.
DOI: 10.1016/j.pt.2016.05.015
Sojka D., Pytelková J., Perner J., Horn M., Konvičková J., Schrenková J., Mareš M., Kopáček P. (2016) Multienzyme degradation of host serum albumin in ticks Ticks and Tick-borne Diseases 7: 603-613.
DOI: 10.1016/j.ttbdis.2015.12.014
Hammoudi P., Jacot D., Mueller C., Di Cristina M., Dogga S., Marq J., Romano J., Tosetti N., Dubrot J., Emre Y., Lunghi M., Coppens I., Yamamoto M., Sojka D., Pino P., Soldati-Favre D. (2015) Fundamental Roles of the Golgi-Associated Toxoplasma Aspartyl Protease, ASP5, at the Host-Parasite Interface PLoS Pathogens 11: e1005211.
DOI: 10.1371/journal.ppat.1005211
Sojka D., Franta Z., Horn M., Caffrey C., Mareš M., Kopáček P. (2013) New insights into the machinery of blood digestion by ticks Trends in parasitology 29: 276-285.
DOI: 10.1016/j.pt.2013.04.002
Sojka D., Franta Z., Frantová H., Bartošová P., Horn M., Váchová J., O'donoghue A., Eroy-Reveles A., Craik C., Knudsen G., Caffrey C., Mckerrow J., Mareš M., Kopáček P. (2012) Characterization of the gut-associated cathepsin D hemoglobinase from the tick Ixodes ricinus (IrCD1). Journal of Biological Chemistry 287: 21152–21163.
DOI: 10.1074/jbc.M112.347922
Franta Z., Sojka D., Frantová H., Dvořák J., Horn M., Srba J., Talacko P., Mareš M., Schneider E., Craik C., Mckerrow J., Caffrey C., Kopáček P. (2011) IrCL1-The haemoglobinolytic cathepsin L of the hard tick, Ixodes ricinus. International Journal for Parasitology 41: 1253–1262.
DOI: 10.1016/j.ijpara.2011.06.006
Sojka D., Francischetti I., Calvo E., Kotsyfakis M. (2011) Cysteine proteases from bloodfeeding arthropod ectoparasites. Advances in experimental medicine and biology 712: 177–191.
DOI: 10.1007/978-1-4419-8414-2_11
Franta Z., Frantová H., Konvičková J., Horn M., Sojka D., Mareš M., Kopáček P. (2010) Dynamics of digestive proteolytic system during blood feeding of the hard tick Ixodes ricinus. Parasites & Vectors 3: 119.
DOI: 10.1186/1756-3305-3-119
Štefanič S., Dvořák J., Horn M., Braschi S., Sojka D., Ruelas D., Suzuki B., Lim K., Hopkins S., Mckerrow J., Caffrey C. (2010) RNA Interference in Schistosoma mansoni Schistosomula: Selectivity, Sensitivity and Operation for Larger-Scale Screening. PLoS Neglected Tropical Diseases 4: e850.
DOI: 10.1371/journal.pntd.0000850
Burešová V., Hajdušek O., Franta Z., Sojka D., Kopáček P. (2009) IrAM-An alpha2-macroglobulin from the hard tick Ixodes ricinus: characterization and function in phagocytosis of a potential patogen Chryseobacterium indologenes Developmental and Comparative Immunology 33: 489-498.
DOI: 10.1016/j.dci.2008.09.011
Hajdušek O., Sojka D., Kopáček P., Burešová V., Franta Z., Šauman I., Winzerling J., Grubhoffer L. (2009) Knockdown of proteins involved in iron metabolism limits tick reproduction and development. PNAS USA 106: 1033-1038.
DOI: 10.1073/pnas.0807961106

Documents to download:
2009-PNAS (pdf)
Horn M., Nussbaumerová M., Šanda M., Kovářová Z., Srba J., Franta Z., Sojka D., Bogyo M., Caffrey C., Kopáček P., Mareš M. (2009) Hemoglobin digestion in blood-feeding ticks: mapping a multipeptidase pathway by functional proteomics. Chemistry & Biology 16: 1053-1063.
DOI: 10.1016/j.chembiol.2009.09.009
Ovat A., Muindi F., Fagan C., Brouner M., Hansell E., Dvořák J., Sojka D., Kopáček P., Mckerrow J., Caffrey C., Powers J. (2009) Aza-peptidyl Michael acceptor and epoxide inhibitors-potent and selective inhibitors of Schistosoma mansoni and Ixodes ricinus legumains (asparaginyl endopeptidases). Journal of Medicinal Chemistry 52: 7192-7210.
DOI: 10.1021/jm900849h
Götz M., James K., Hansell E., Dvořák J., Seshaadri A., Sojka D., Kopáček P., Mckerrow J., Caffrey C., Powers J. (2008) Aza-peptidyl Michael acceptors. A new class of potent and selective inhibitors of asparaginyl endopeptidases (legumains) from evolutionarily diverse pathogens. Journal of Medicinal Chemistry 51: 2816-2832.
DOI: 10.1021/jm701311r
Sojka D., Franta Z., Horn M., Hajdušek O., Caffrey C., Mareš M., Kopáček P. (2008) Profiling of proteolytic enzymes in the gut of the tick Ixodes ricinus reveals an evolutionarily conserved network of aspartic and cysteine peptidases. Parasites & Vectors 0-0.
DOI: 10.1186/1756-3305-1-7
Sojka D., Hajdušek O., Dvořák J., Sajid M., Franta Z., Schneider E., Craik C., Vancová M., Burešová V., Bogyo M., Sexton K., Mc Kerrow J., Caffrey C., Kopáček P. (2007) IrAE – An asparaginyl endopeptidase (legumain) in the gut of the hard tick Ixodes ricinus. International Journal for Parasitology 37: 713-724.
DOI: 10.1016/j.ijpara.2006.12.020
Grunclová L., Horn M., Vancová M., Sojka D., Franta Z., Mareš M., Kopáček P. (2006) Two secreted cystatins of the soft tick Ornithodoros moubata: differential expression pattern and inhibitory specificity. Biological Chemistry 387: 1635-1644.
DOI: 10.1515/BC.2006.204

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