| Total found: 74 records |
Cadena L.,
Gahura O.,
Panicucci B.,
Panicucci Zíková A.,
Hashimi H. (2021) Mitochondrial Contact Site and Cristae Organization System and F1FO-ATP Synthase Crosstalk Is a Fundamental Property of Mitochondrial Cristae mSphere
16: e0032721.
DOI: 10.1128/mSphere.00327-21
Documents to download:
Cadena_2021_mSphere (pdf)
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Doleželová E., Klejch T., Špaček P., Slapničková M., Guddat L., Hocková D.,
Zíková A. (2021) Acyclic nucleoside phosphonates with adenine nucleobase inhibit Trypanosoma brucei adenine phosphoribosyltransferase in vitro Scientific Reports
11: 13317.
DOI: 10.1038/s41598-021-91747-6
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Gahura O.,
Hierro-Yap C.,
Zíková A. (2021) Redesigned and reversed: architectural and functional oddities of the trypanosomal ATP synthase Parasitology
148: 1151–1160.
DOI: 10.1017/S0031182021000202
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Hierro-Yap C., Šubrtová ,
Gahura O.,
Panicucci B., Dewar C., Chinopoulos C., Schnaufer A.,
Zíková A. (2021) Bioenergetic consequences of FoF1-ATP synthase/ATPase deficiency in two life cycle stages of Trypanosoma brucei Journal of Biological Chemistry
296: 100357.
DOI: 10.1016/j.jbc.2021.100357
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Kalčic F., Frydrych J.,
Doleželová E.,
Slapničková M., Pachl P., Slavětínská L.P., Hocková D.,
Zíková A., Janeba Z. (2021) C1'-Branched acyclic nucleoside phosphonates mimicking adenosine monophosphate: Potent inhibitors of Trypanosoma brucei adenine phosphoribosyltransferase European Journal of Medicinal Chemistry
225: 113798.
DOI: 10.1016/j.ejmech.2021.113798
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Nguyen V.H., Tichý M., Rožánková S., Pohl R.,
Doleželová E., Tloušťová E.,
Slapničková M.,
Zíková A., Hocek M. (2021) Synthesis and anti-trypanosomal activity of 3'-fluororibonucleosides derived from 7-deazapurine nucleosides Bioorganic & Medicinal Chemistry Letters
40: 127957.
DOI: 10.1016/j.bmcl.2021.127957
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Perlíková P., Krajczyk A.,
Doleželová E.,
Slapničková M., Milisavljevic N., Slavětínská L.P., Tloušt'ová E., Gurská S., Džubák P., Hajdúch M.,
Panicucci Zíková A., Hocek M. (2021) Synthesis and Antitrypanosomal Activity of 6-Substituted 7-Methyl-7-deazapurine Nucleosides ACS Infectious Diseases
7: 917–926.
DOI: 10.1021/acsinfecdis.1c00062
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Serricchio M.,
Hierro-Yap C., Schädeli D., Hamidane H.B., Hemphill A., Graumann J.,
Panicucci Zíková A., Bütikofer P. (2021) Depletion of cardiolipin induces major changes in energy metabolism in Trypanosoma brucei bloodstream forms Faseb Journal
35: e21176.
DOI: 10.1096/fj.202001579RR
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Tobiasson V.,
Gahura O., Aibara S., Baradaran R.,
Panicucci Zíková A., Amunts A. (2021) Interconnected assembly factors regulate the biogenesis of mitoribosomal large subunit Embo Journal
e106292.
DOI: 10.1101/2020.06.28.176446
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Villafraz O., Biran M., Pineda E., Plazolles N., Cahoreau E., Ornitz Oliveira Souza R., Thonnus M., Allmann S., Tetaud E., Rivière L., Silber A.M., Barrett M.P.,
Zíková A., Boshart M., Portais J.C., Bringaud F. (2021) Procyclic trypanosomes recycle glucose catabolites and TCA cycle intermediates to stimulate growth in the presence of physiological amounts of proline PLoS Pathogens
17: 1009204.
DOI: 10.1371/journal.ppat.1009204
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Aphasizheva I., Alfonzo J., Carnes J., Cruz-Reyes J., Göringer H.U., Hajduk S.,
Lukeš J., Madison-Antenucci S., Maslov D., Mcdermott S., Ochsenreiter T., Read L., Salavati R., Schnaufer A., Schneider A., Simpson L., Stuart K., Yurchenko V., Zhou Z.H.,
Panicucci Zíková A., Zhang L., Zimmer S., Aphasizhev R. (2020) Lexis and Grammar of Mitochondrial RNAProcessing in Trypanosomes Trends in Parasitology
36: 4.
DOI: 10.1016/j.pt.2020.01.006
Documents to download:
Aphasizheva_2020_TrendsinParasitology (pdf)
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Doleželová E.,
Kunzová M., Dejung M., Levin M.,
Panicucci B., Regnault C., Janzen C., Barrett M.P., Butter F.,
Panicucci Zíková A. (2020) Cell-based and multi-omics profiling reveals dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei Plos Biology
18: e3000741.
DOI: 10.1371/journal.pbio.3000741
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Lukeš J., Danek P., Alejo-Valle O., Potůčková E.,
Gahura O., Heckl D., Stárková J., Starý J., Mejstříková E., Alberich-Jorda M., Zuna J., Trka J., Klusmann J.-H., Zaliová M. (2020) Chromosome 21 gain is dispensable for transient myeloproliferative disorder driven by a novel GATA1 mutation Leukemia
34: 2503-2508.
DOI: 10.1038/s41375-020-0769-1
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Smith J.T.,
Doleželová E., Tylec B., Bard J.E., Chen R., Sun Y.,
Panicucci Zíková A., Read L. (2020) Developmental regulation of edited CYb and COIII mitochondrial mRNAs is achieved by distinct mechanisms in Trypanosoma brucei Nucleic Acids Research
48: 8704–8723.
DOI: 10.1093/nar/gkaa641
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Zoltner M., Campagnaro G.D.,
Taleva G., Burrell A., Cerone M., Leung K., Achcar F., Horn D., Vaughan S., Gadelha C.,
Panicucci Zíková A., Barrett M.P., de Koning H.,
Field M. (2020) Suramin exposure alters cellular metabolism and mitochondrial energy production in African trypanosomes Journal of Biological Chemistry
295: 8331-8347.
DOI: 10.1074/jbc.RA120.012355
Documents to download:
Zoltner_2020_JBC (pdf)
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Gahura O.,
Panicucci Zíková A. (2019) Isolation of F1-ATPase from the Parasitic Protist Trypanosoma brucei Journal of visualized experiments : JoVE
22: e58334.
DOI: 10.3791/58334
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Nenarokova A., Záhonová K., Krasilnikova M.,
Gahura O., McCulloch R.,
Zíková A.,
Yurchenko V.,
Lukeš J. (2019) Causes and effects of loss of classical nonhomologous end joining pathway in parasitic eukaryotes mBio
10: e01541-19.
DOI: 10.1128/mBio.01541-19
Documents to download:
Nenarokova_et al._2019 (pdf)
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Terán D.,
Doleželová E., Keough D., Hocková D.,
Panicucci Zíková A., Guddat L. (2019) Crystal structures of Trypanosoma brucei hypoxanthine – guanine – xanthine phosphoribosyltransferase in complex with IMP, GMP and XMP FEBS Journal
286: 4721-4736.
DOI: 10.1017/S0022149X19000737
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Doleželová E., Terán D.,
Gahura O., Kotrbová Z., Procházková M., Keough D., Špaček P., Hocková D., Guddat L.,
Zíková A. (2018) Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery PLOS Neglected Tropical Diseases
DOI: 10.1371/journal.pntd.0006301
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Gahura O.,
Panicucci B., Váchová Hana, Walker John E.,
Zíková A. (2018) Inhibition of F1 -ATPase from Trypanosoma brucei by its regulatory protein inhibitor TbIF1 FEBS Journal
DOI: 10.1111/febs.14672
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